Zusammenfassung Die X‑chromosomale Hypophosphatämie (X-linked hypophosphatemic rickets, XLH, OMIM # 307800) ist eine seltene Erkrankung des Knochenstoffwechsels, die mit einem ausgeprägten Phosphatverlust und oftmals schwerer Beeinträchtigung der Lebensqualität einhergeht. Durch einen bislang noch ungeklärten Pathomechanismus kommt es durch Mutationen in Endopeptidase PHEX zu einer vermehrten P...

The bacteriocin BacR1 was purified from culture supernatant of Staphylococcus aureus UT0007 by sequential ammonium sulfate precipitation, cation-exchange chromatography, and C4 reverse-phase chromatography steps. Mass spectrographic analysis indicated that the purified peptide has a molecular mass of 3,338 Da. It is resistant to environmental conditions, retaining full biological activity after...

A 3.2 kb plasmid pCR2 was isolated from Corynebcterium renale which harbours four cryptic plasmids. This plasmid was used for the construction of a range of cloning and expression vectors for E.co/i. This previously uncharacterized plasmid was first sequenced by cloning its fragments into pUC19. The complete nucleotide sequence thus obtained was annotated and submitted to GENEBANK (Accession No...

OBJECTIVE To determine the mineral composition of calculi, anatomic locations of the calculi, and findings of urinalysis and bacteriologic culture of urine and calculi in guinea pigs with urolithiasis. DESIGN Cross-sectional study. ANIMALS 127 guinea pigs. PROCEDURES Records of urinary calculi that had been submitted to the University of California Stone Laboratory from 1985 through 2003 ...