BACKGROUND The effect of beta blockers on myocardial blood flow (MBF) under vasodilators has been studied in several SPECT and PET myocardial perfusion imaging (MPI) studies with divergent results. The present study evaluated the effect of a beta blocker withdrawal on quantitative adenosine MBF and on MPI results. METHODS Twenty patients with beta blockers and CAD history were studied with qu...

BACKGROUND The development of ST-segment depression during adenosine myocardial perfusion imaging (MPI) has been shown to be an independent predictor of subsequent cardiac events and worse outcome, particularly in association with ischemic defects. However, the prognostic significance of ST-segment depression with adenosine in patients with normal MPI is not known. METHODS AND RESULTS We perf...

INTRODUCTION Mild ischemia in the inferolateral wall on myocardial perfusion imaging is seen frequently in practice. The aim of this study is to assess the importance of the above issue on myocardial perfusion SPECT with coronary angiography. PATIENTS AND METHODS All patients enrolled in this study exhibited mild ischemia of the inferolateral wall on myocardial single photon emission computed...

BACKGROUND Ischaemic heart disease (IHD) is a major health problem today. However the focus has shifted primarily to angiographically detecting epicardial vessel stenoses, and ways and means of surgically correcting the blocks. Patients are often not fully evaluated for cardiac function, and diastolic dysfunction of heart, which is often an earlier manifestation than systolic dysfunction, goes ...

UNLABELLED This study was designed to assess the prognostic value of stress myocardial perfusion SPECT with electrocardiographic (ECG) gating in patients undergoing noncardiac surgical treatment. METHODS The study included 481 consecutive patients who underwent noncardiac surgery and had been referred for preoperative myocardial perfusion scintigraphy. Myocardial scintigraphy used (99m)Tc-lab...

Received 7/31/2006; revised 9/1/2006; accepted 9/5/2006. For correspondence or reprints contact: Ming-Hsien Lin, M.D., Department of Nuclear Medicine, Taipei City Hospital, Zhongxiao Branch. 87 Tong De Road, Nan Gang District, Taipei 115, Taiwan. Tel: (886)2-27861288 ext. 8089, Fax: (886)226534501, E-mail: [email protected] Background: Peripheral arterial occlusive disease (PAOD) has become mo...

BACKGROUND Left Bundle Branch Block (LBBB) is a known cause of false positive results in myocardial perfusion studies. We aimed at investigation of correlation between degree of severity of perfusion defect on cardiac Single Photon Emission Computed Tomography (SPECT) and presence of coronary artery disease on angiography in patients with LBBB. STUDY DESIGN This was an analytical study and wa...

myocardial ischemia (mi) resulting in infarction is an important cause of mortality and morbidity worldwide. acute ischaemia rapidly impairs myocardial contractile function. myocardial dysfunction persisting for several hours after transient non-lethal ischaemia, eventually resulting in full functional recovery is termed as myocardial stunning. hibernation is now thought to be the consequence o...

Clinical data on 3,911 patients were collected from 64 individual investigators to evaluate the safety of intravenous dipyridamole-thallium imaging as an alternative to exercise thallium imaging for the evaluation of coronary artery disease. There were two deaths because of myocardial infarctions, two nonfatal myocardial infarctions, and six cases of acute bronchospasm. Chest pain occurred in 7...

OBJECTIVES The goal of this study was to examine the effect of acute beta-blockade on dipyridamole Tc-99m sestamibi myocardial perfusion imaging (DMPI). BACKGROUND Studies suggest that antianginal drugs may reduce the presence and severity of myocardial perfusion defects with dipyridamole stress. However, there are no data regarding specific drugs. METHODS Patients with catheterization-prov...