A new approach to the simultaneous measurement of hydrogen evolution reaction (HER) and elemental dissolution rates is presented applied galvanized steel coatings with HCl solution. Dissolution profiles revealed several kinetic regimes including intact coating, nanometric Fe2Al5 intermetallic layer, corrosion substrate. The HER Zn were in excellent agreement, quantities interfacial Fe Al consis...

[1] Microscopic simulations of fracture dissolution are reported, taking account of the explicit topography of the pore space, the transport of reactants and products, and the chemical kinetics at the solid surfaces. A three-dimensional numerical model has been constructed, in which the fluid velocity field is calculated with an implicit lattice-Boltzmann method, and the transport of dissolved ...

Introduction Ingested lipids could offer valuable opportunities for enabling oral drug delivery, as approximately 4070% of all new drug candidates have been estimated to have very poor water solubility and are expected to exhibit low bioavailability when orally dosed. For hydrophobic drug molecules, the dissolution process in water is likely the limiting step of overall oral absorption. Therefo...

Ongoing global warming induced by anthropogenic emissions has opened the debate as to whether geoengineering is a ‘quick fix’ option. Here we analyse the intended and unintended effects of one specific geoengineering approach, which is enhanced weathering via the open ocean dissolution of the silicate-containing mineral olivine. This approach would not only reduce atmospheric CO2 and oppose sur...

Oxidative dissolution controls uranium release to (sub)oxic pore waters from biogenic uraninite produced by natural or engineered processes, such as bioremediation. Laboratory studies show that uraninite dissolution is profoundly influenced by dissolved oxygen (DO), carbonate, and solutes such as Ca(2+). In complex and heterogeneous subsurface environments, the concentrations of these solutes v...

PURPOSE To develop a bio-assay that would be able to directly test gastrointestinal and/or dissolution samples to determine lipase activity and inhibition by Orlistat. METHODS Enzyme assays were performed with porcine pancreatic lipase and para-Nitrophenyl Palmitate (pNPP) in pH 8.0 reaction buffer at 37°C. Substrate hydrolysis was monitored by absorbance changes at 410 nm. The dissolution of...

Experiments to assess metabolic reductive dechlorination (chlororespiration) at high concentration levels consistent with the presence of free-phase tetrachloroethene (PCE) were performed using three PCE-to-cis-1,2-dichloroethene (cis-DCE) dechlorinating pure cultures (Sulfurospirillum multivorans, Desulfuromonas michiganensis strain BB1, and Geobacter lovleyi strain SZ) and Desulfitobacterium ...

β-Tricalcium phosphate (β-TCP) is an attractive ceramic for bone tissue repair because of its similar composition to bone mineral and its osteoconductivity. However, compared with other ceramics β-TCP has a rapid and uncontrolled rate of degradation. In the current study β-TCP granules were mineral coated with the aim of influencing the dissolution rate of β-TCP, and also to use the coating as ...

The present investigation includes the preparation of liquid filling formulations for soft gels using an antihypertensive drug, valsartan (VAL), in order to improve its dissolution properties and thereby its bioavailability. Formulations were prepared using excipients like polyethylene glycol 400 (PEG 400), propylene glycol (PG), polyvinylpyrrolidone (PVP K-30), antioxidants, ethanol, and purif...

A study of sulfur-rich sludge (71.6% pyrite) dissolution at alkaline conditions (pH ca.9) was investigated using non-stirred and stirred flow-through experiments at room temperature (26 ± 1.2oC) and O2 partial pressure of 0.20 atm. The dissolution rate of pyrite-rich sludge was calculated based on the S release (aqueous SO4) at the steady-state. Results show that: (1) in the nonstirred reactor ...