Relaxin, a peptide hormone secreted by the corpus luteum during pregnancy, exerts actions on reproductive tissues such as the pubic symphysis, uterus, and cervix. It may also influence body fluid balance by actions on the brain to stimulate thirst and vasopressin secretion. We mapped the sites in the brain that are activated by i.v. infusion of a dipsogenic dose of relaxin (25 microg/h) by immu...

Somponpun, Suwit J., Alan Kim Johnson, Terry Beltz, and Celia D. Sladek. Estrogen receptorexpression in osmosensitive elements of the lamina terminalis: regulation by hypertonicity. Am J Physiol Regul Integr Comp Physiol 287: R661–R669, 2004. First published May 13, 2004; 10.1152/ajpregu.00136.2004.—The subfornical organ (SFO), median preoptic nucleus (MnPO), and organum vasculosum lamina termi...

It has previously been reported (Emerson and Cushing, 1946; Emerson, 1947) that the so-called sulfonamide-requiring mutant strain of Neurospora (strain E-15172, hereafter designated by the symbol "sfo") does not grow on minimal medium at 35 C, that the addition of sulfanilamide (SA) permits maximum growth at that temperature and augments the growth occurring at lower temperatures, and that the ...

Between February 2006 and October 2009, 38 patients in different wards at the A Coruña University Hospital (northwest Spain) were either infected with or colonized by an epidemic, multidrug-resistant (MDR), and extended-spectrum-β-lactamase (ESBL)-producing strain of Enterobacter cloacae (EbSF), which was susceptible only to carbapenems. Semiautomated repetitive extragenic palindromic sequence-...

The preparation of flavored vegetable oils using spice and herb plants is considered to be an indispensable opportunity for the application these plants. In present exploration, sunflower oil (SFO) samples by Mentha spicata L. (spearmint) were prepared maceration method (MM) ultrasound-assisted (UM). antioxidant effects, sensory evaluation oxidative stability during accelerated storage; physico...

The subfornical organ (SFO), median preoptic nucleus (MnPO), and organum vasculosum lamina terminalis (OVLT), which are associated with the lamina terminalis, are important in the control of body fluid balance. Neurons in these regions express estrogen receptor (ER)-alpha, but whether the ER-alpha neurons are activated by hypertonicity and whether hypertonicity regulates ER-alpha expression are...

We report the results of a search for the double-peaked blue-skewed infall signature in the bright-rimmed cloud core SFO 11NE SMM1. Observations of the optically thick HCO and optically thin H13CO+ J = 3−2 lines reveal that there is indeed a characteristic double-peaked line profile, but skewed to the red rather than the blue. Modelling of the dust continuum emission and line profiles show that...

Twenty-five neurons in the region of the nucleus of the solitary tract (NTS) were antidromically activated by electrical stimulation of the subfornical organ (SFO) in male rats under urethane anesthesia. Microiontophoretically applied bicuculline, a gamma-aminobutyric acid (GABA)(A) antagonist, but not phaclofen, a GABA(B) antagonist, attenuated the post-antidromic inhibitory response evoked by...

Honda, Eiko, Kentaro Ono, Shinji Kataoka, and Kiyotoshi Inenaga. Activation of subfornical organ neurons in rats through preand postsynaptic -adrenoceptors. Am J Physiol Regul Integr Comp Physiol 290: R1646–R1653, 2006. First published February 2, 2006; doi:10.1152/ajpregu.00801.2004.—The effects of noradrenaline (NA) and its analogs on subfornical organ (SFO) neurons in rat slice preparations ...

The brain senses circulating levels of angiotensin II (AngII) via circumventricular organs, such as the subfornical organ (SFO), and is thought to adjust sympathetic nervous system output accordingly via this neuro-hormonal communication. However, the cellular signaling mechanisms involved in these communications remain to be fully understood. Previous lesion studies of either the SFO, or the d...