Previously we reported that Src-associated-substrate-during-mitosis-of-68kDa (Sam68/KHDRBS1) is pivotal for DNA damage-stimulated NF-κB transactivation of anti-apoptotic genes (Fu et al., 2016). Here we show that Sam68 is critical for genotoxic stress-induced NF-κB activation in the γ-irradiated colon and animal and that Sam68-dependent NF-κB activation provides radioprotection to colon epithel...

Several optimization approaches have been compared to optimally locate and power size the RBSs of a GSM network, in order to efficiently dimension the transceiver properties without exceeding radioprotection limits. Such optimization tools are embedded within a planning system where several modules interact, exploiting each other’s features. In particular, the optimum planning tools exploit the...

Cette étude, réalisée par l’IRSN (Institut de Radioprotection et Sûreté Nucléaire) dans le cadre d’une demande l’ASN (Autorité Nucléaire), concerne la caractérisation des formes physico-chimiques composés radioactifs rejetés les installations françaises fabrication radiopharmaceutiques au moyen d’un cyclotron. Elle vise à disposer meilleure connaissance sur effluents gazeux ces installations. é...

background: ionizing radiation causes deleterious effects on living system mainly due to oxidative damages of macromolecules and protein is the major target due to its abundance. the aim of this study was to investigate the effects of ionizing radiation induced changes in the molecular properties of bovine serum albumin (bsa) its secondary and tertiary structures, degradation, cross linking and...

abstractbackground: radioprotective effects of famotidine, an antagonist of h2 receptor clinically used for peptic ulcer treatment, was previously shown on radiation-induced micronuclei and chromosomal aberration in human peripheral blood lymphocytes and mouse bone marrow cells. this study was conducted to investigate radioprotective property of famotidine against radiation induced apoptosis in...