Blood donor screening for HIV antibody was carried out at Blood Transfusion Service of Jinnah Postgraduate Medical Centre. Sera of 1655 blood donors were tested by Enzyme linked Immuno-Sorbent Assay (Abbott recombinant HIV-1-EIA) from March, 1987 to December, 1989. Initial reactivity was noted in seven cases, of which three were repeatedly reactive. When these were tested by western blot at Nat...

The biological methyl donor S-adenosyl-L-methionine [(S,S)-AdoMet] can spontaneously break down under physiological conditions to form the inactive diastereomer (R,S)-AdoMet, which may interfere with cell function. Although several lower organisms metabolize (R,S)-AdoMet via homocysteine methyltransferases, it is unclear how mammals deal with it. In this paper, we show that the mouse liver extr...

A dihydroxotin(IV) porphyrin functionalized single-walled carbon nanotubes (SWNTs) nanohybrid is obtained. Solubility of the nanohybrid in organic solvents is determined by UV-Vis-NIR absorption spectroscopy. Electron absorption and fluorescence spectra investigations demonstrate that efficient electron transfer occurs within the nanohybrid at the photoexcited state and the charge-separated sta...

Recent theory has found that native defects such as the O vacancy V(O) and Zn interstitial Zn(I) have high formation energies in n-type ZnO and, thus, are not important donors, especially in comparison to impurities such as H. In contrast, we use both theory and experiment to show that, under N ambient, the complex Zn(I)-N(O) is a stronger candidate than H or any other known impurity for a 30 m...

BACKGROUND Keeping waiting time at blood donation short is important for making donation a good experience for the donors and hence to motivate for repeat donations. At the Blood Bank of Oslo, fixed appointments are used, and few donors arrive without appointments. On average, 59 percent of scheduled donors arrive, but day-to-day variations are large. Methods for predicting the number of donors...

BACKGROUND Avian influenza A (H7N9) virus has emerged recently and continues to cause severe disease with a high mortality rate in humans prompting the development of candidate vaccine viruses. Live attenuated influenza vaccines (LAIV) are 6:2 reassortant viruses containing the HA and NA gene segments from wild type influenza viruses to induce protective immune responses and the six internal ge...

Donor selection for allografting of a non-paired vital organ, such as the heart, is necessarily limited to cadaveric or possibly xenogeneic sources. In contrast, because of the presence in most normal persons of two kidneys – each with a physiological reserve capable of providing four times the minimal required function – renal transplantation has become an accepted medical procedure using cada...

OBJECTIVE The aim of this study was to emphasize the significance of internal audits of the blood donor selection process and documentation in a resource-limited country by assessing compliance with the established protocols, and to identify weak areas in the process. MATERIALS AND METHODS This audit reviewed the donor selection process at the blood bank of Liaquat National Hospital & Medical...