To store apples, refrigerate them in a plastic bag or in the crisper drawer. Check the stored apples often – one bad apple can spoil the whole bag! When you cut a raw apple, it may turn dark. To prevent this, dip the pieces in a fruit juice like lemon, orange, grapefruit, or pineapple before combining with other ingredients. Right now, apples are in pretty good supply. Whether you buy locally g...

It is well known that eating fruits and vegetables lowers the risk of chronic diseases such as heart disease and cancer. The question of what is/are the active ingredient(s) is still unresolved. The initial hypothesis was that the antioxidant vitamins were responsible. However, recently the polyphenols have been investigated since they have been found to have beneficial properties such as being...

Six severe and six mild Florida isolates of citrus tristeza virus (CTV) were used to evaluate the transmission efficiency of the virus from grapefruit seedlings by single brown citrus aphids (Toxoptera citricida Kirkaldy) (BrCA) from colonies initiated by aphids obtained from citrus groves in Fort Pierce, Fla. The transmission rate to 2120 receptor plants [‘Mexican’ lime (Citrus aurantifolia)] ...

Tacrolimus is a well-known potent immunosuppressant agent, which has various drug-drug or food-drug interactions. Previously, we found a renal transplant recipient who increased tacrolimus blood concentrations after ingestion of pomelo as a rare case. So, we investigated the effect of pomelo after its administration for one day or 3 consecutive days on the pharmacokinetics of tacrolimus in rats...

a US Fish and Wildlife Service, Bozeman Fish Technology Center, Bozeman, MT 59715, USA b Montana State University, Department of Animal and Range Sciences, Bozeman, MT 59715, USA c USDA-ARS, Trout Grains Project, Bozeman Fish Technology Center, Bozeman, MT 59715, USA d ADM Research, 1001 N Brush College Road, Decatur, IL 62521, USA e USDA-ARS, Harry K. Dupree Stuttgart National Aquaculture Rese...

Fourteen triethylamine derivatives including the 2-(4-chlorophenylthio)triethylamine (CPTA) were all found to be effective in inducing the formation of lycopene in Marsh white seedless grapefruit (Citrus paradisi, Rutaceae); however, they differed in the degree of effectiveness. The structural feature necessary for inducer activity appeared to be the tertiary alkylamine. Compounds with an S ato...

Grapefruit juice elevates blood levels of some drugs taken orally, primarily by inhibiting intestinal CYP3A4-mediated first-pass metabolism. Two prominent furanocoumarins in the juice, 6',7'-dihydroxybergamottin (DHB) and bergamottin (BG), have been demonstrated as important contributors to grapefruit juice-drug interactions. Using CYP3A4-expressing Caco-2 cells and representative probes from d...

Acknowledgments. We thank Eimile Dougherty (Cedarville University); Sunhali Sharma and Issac V. Greenhut (Plant Pathology, SWFREC, UF); Peter Newman and Lisa Cushman (Citrus Physiology Laboratory, SWFREC, IFAS, UF, Immokalee, FL), for technical assistance. *Corresponding author; phone: (239) 658-3400; fax: (239) 658-3469; email: [email protected] Effect of Salicylic Acid on Oxidative Metabolism du...

A community based cross-sectional study was carried out in rural areas of West Bengal with the aim to assess the prevalence of vitamin A deficiency (VAD) among rural preschool children. Clinical examination was carried out on 9,228 children for the signs and symptoms of VAD and a sub-sample of 590 children were covered for the estimation of blood vitamin A levels using dried blood spot (DBS) me...

Fruit juice-drug interactions involving drug transporters and metabolic enzymes have been studied with various citrus fruit juices. The collective data led us to hypothesize that the modulating activity of citrus fruit juices on cellular transport and metabolic pathways is dependent on the dominant flavonoid pattern and taxonomy of the citrus fruits. This hypothesis has important implications g...