نتایج جستجو برای: drug industry

تعداد نتایج: 773051  

Journal: :BMJ 2016
Courtney Davis Joel Lexchin Tom Jefferson Peter Gøtzsche Martin McKee

After the thalidomide tragedy governments in Europe and North America established new requirements for drug testing intended to protect the public from ineffective and unsafe drugs. As no drugs are entirely safe, regulators must determine whether manufacturers have provided enough evidence to show that drugs’ benefits outweigh their harms. Precisely how high the evidence bar should be set for m...

2016
Wolfgang Wein

Correspondence to Dr Wolfgang Wein; wolfgang. [email protected] ISSUE 1: DEMOGRAPHICS Currently, the world population is heading for an 11 billion people peak in the next decades. Owing to the successful and victorious efforts and strategies of the academia, pharmaceutical industry and regulators, the average life expectancy of the European population will be close to a hundred years by the m...

Journal: :Drug discovery today 2009
Cathy J Tralau-Stewart Colin A Wyatt Dominique E Kleyn Alex Ayad

The re-focusing of pharmaceutical industry research away from early discovery activities is stimulating the development of novel models of drug discovery, notably involving academia as a 'front end'. In this article the authors explore the drivers of change, the role of new entrants (universities with specialised core facilities) and novel partnership models. If they are to be sustainable and d...

Journal: :PLoS Medicine 2005
Smith Richard

September 2005 | Volume 2 | Issue 9 | e241 Britain’s House of Commons Health Committee has recently recommended a fundamental realignment of the relationships between the pharmaceutical industry and government, regulators, doctors, the health service, and patients [1]. The committee said that the industry has interdigitated itself into every aspect of health care, and that government and others...

Journal: :Cadernos de saude publica 2008
Anna Haydée Lanzillotti Jannuzzi Alexandre Guimarães Vasconcellos Cristina Gomes de Souza

Different forms of protection for inventions in the pharmaceutical industry point to strategies for the perpetuation of patent protection. Based on a literature review showing the specificities of patenting in the industry, the article provides a brief history of drug patents in Brazil, a discussion of patentable and non-patentable inventions, and the modalities and traits of patent protection ...

Journal: :BMJ 2008
Bob Burton

A new report is calling for changes in the conduct of clinical trials in the United States to reduce disparities of age, sex, race, and comorbidity. The goal is to give a more representative picture of the benefits and risks of a treatment across the entire population but particularly among those who bear the greatest burden of the morbidity. The eliminating disparities in clinical trials (EDIC...

Journal: :PDA journal of pharmaceutical science and technology 2015
David Bain Diane Hardy Brian L Bell Ren-Yo Forng Michael Knight Anita Bawa Stephanie Ramsey Christine Arbesser-Rastburg Mousumi Paul Christopher Ton Fran Leira Claudia Roman Kim McFarland David Phillips Jean Stuckey Christian Bauer Andres J Calvo

Diane Hardy, Chief Microbiologist, Regeneron Brian L. Bell, Senior Scientist, Bristol-Myers Squibb Ren-Yo Forng, Site Microbiologist, Astra Zeneca Michael Knight, Senior Manager QC Microbiology, Genentech Anita Bawa, Director QC, Bayer Stephanie Ramsey, Manager Quality Systems, Baxter Christine Arbesser-Rastburg, Director Quality Operations / Microbiology, Baxter Mousumi Paul, Associate Directo...

Journal: :Journal of pharmaceutical and biomedical analysis 1983
P M Bersier

Essential to the renewal of interest in polarography and voltammetry in the 1970s were the availability of reliable polarographs offering the pulse mode, with sensitivity down to lo-‘-lo-* M and h’gh 1 er resolving power; a better understanding of the electrode processes of compounds of pharmaceutical interest (active agents, excipients, additives, antioxidants, etc.); and the application of ox...

Journal: :Journal of clinical pharmacology 2008
J Andrew Williams Tommy Andersson Tommy B Andersson Rebecca Blanchard Martin Otto Behm Nadine Cohen Timi Edeki Monique Franc Kathleen M Hillgren Keith J Johnson David A Katz Mark N Milton Bernard P Murray Joseph W Polli Deb Ricci Lisa A Shipley Subrahmanyam Vangala Steven A Wrighton

Pharmacogenomic (PGx) research on the absorption, distribution, metabolism, and excretion (ADME) properties of drugs has begun to have impact for both drug development and utilization. To provide a cross-industry perspective on the utility of ADME PGx, the Pharmaceutical Research and Manufacturers of America (PhRMA) conducted a survey of major pharmaceutical companies on their PGx practices and...

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