Because of its rapid onset of action, pulmonary administration of levodopa is an interesting alternative to oral administration for the rescue treatment of Parkinson's disease patients in an off period. We studied the ability of Parkinson's disease patients to operate a dry powder inhaler (DPI) correctly during an off period. We used an instrumented test inhaler with three different resistances...

BACKGROUND In patients receiving inhaled medication, dissatisfaction with and difficulty in using the inhaler can affect treatment adherence. The incidence of handling errors is typically higher in the elderly than in younger people. The aim of the study was to assess inhaler preference for and handling errors with the ELLIPTA® dry powder inhaler (DPI), (GSK), compared with the established BREE...

OBJECTIVE To evaluate treatment compliance and use of inhaled medications of patients with asthma receiving complementary pharmaceutical care. METHODS A controlled prospective parallel study involving a study group and a control group. We selected 60 patients with persistent asthma and using metered-dose inhalers (MDIs), dry powder inhalers (DPIs) or both. The patients were evaluated three ti...

In sandy soils of the southeastern USA coastal plains, crop production is limited by low water holding capacity and compacted soil layers that reduce root growth and productivity. Polyacrylamide (PAM) was added to sandy coastal plain soils to improve physical properties and yield. Soils were amended with linear and cross-linked PAMs. Treatments and controls included the following: (1) spraying ...

Several dry processing techniques are assessed to elaborate metallic nanocomposite powders dedicated powder-bed-based (PBB) additive manufacturing as laser-powder bed fusion (L-PBF) and Binder Jetting (BJ). Electrostatic assembly of nanosized silicon carbide (35 nm) particles at the surface gas atomized aluminium (15-53 ?m) is performed using mixers covering a range mixing energy from rotative ...