Despite a large body of basic science and clinical research and clinical experience with thousands of infants over nearly 6 decades,(1) there is still uncertainty and controversy about the significance, evaluation, and management of patent ductus arteriosus in preterm infants, resulting in substantial heterogeneity in clinical practice. The purpose of this clinical report is to summarize the ev...

of the startling and sensational events in medical practice of the century. Yet in actual fact the story only goes back twelve years: for it was in 1939 that Gross in Boston successfully ligatured a patent ductus arteriosus, an operation which proved to be the advent of great things to come. It is not my intention here to go into the surgical details of the operations which are nowadays perform...

This syndrome – recognized only in the last decade – is still not accepted by the International League Against Epilepsy [6]. Rotavirus has been reported as the most common etiological agent in this condition in different studies [4,5]. However, other organisms have also been reported [3], and it has not been possible to attribute the convulsions to any organism, as yet [2]. The clinical symptom...

BACKGROUND There is clinical equipoise regarding post-operative management of patients with patent ductus arteriosus (PDA) without insertion of a chest drain. This study evaluated post operative outcomes of chest closure with or without a drain following Patent Ductus Arteriosus ligation among childen at Uganda Heart Instritute (UHI). METHODS This was an open label randomized controlled trial...

The pulsed Doppler technique was used to record the flow velocity patterns in the ductus arteriosus and the pulmonary artery in 26 patients with either isolated or complicated patent ductus arteriosus (PDA). In all patients, abnormal Doppler signals indicating left-to-right (L-R) or right-to-left shunt flow or both could be obtained at the site of the ductus arteriosus. These Doppler flow patte...

Patent ductus arteriosus (PDA) is a common diagnosis among extremely premature infants, especially in those with lung disease. Treatments are often used to close the PDA. Despite nearly three decades of research, the question of whether the benefits of treatments to prevent ductal patency or promote closure outweigh the risks of these treatments remains unanswered. The authors rarely use treatm...

Dye dilution and cardiac catheterization technics were used to study 36 patients with a central left-to-right shunt due to patent ductus arteriosus, atrial septal defect or ventricular septal defect. The configuration of dilution curves following injection of dye into an antecubital vein was similar in all instances. Principal abnormalities of the curve were a prolongation of its disappearance ...