An association between malrotation and congenital duodenal webbing is rare. We present our experience with four patients at two centers, and a review of published reports. There are currently 94 reported cases of duodenal pathology associated with malrotation. However, only 15 of the 94 cases (15.9%) include patients with malrotation and a duodenal web. We suggest that nonbilious vomiting in a ...

Failure of duodenal recanalization results in a spectrum of proximal bowel obstruction from stenosis to atresia. Associations between congenital duodenal obstruction and other congenital anomalies have been well documented although the coincidence of duodenal stenosis and duodenal web is incredibly rare, posing a unique diagnostic challenge. We report a case of a full-term 4-day-old female chil...

We present a case of intramural duodenal haematoma caused by inferior vena caval (IVC) filter strut perforation requiring innovative open and endovascular retrieval. A 32-year-old woman presents in shock with dull epigastric pain and non-bilious vomiting. She had previously had an IVC filter for deep venous thrombosis and pulmonary embolism. Computed tomography demonstrated strut perforation in...

It has long been established that various human body secretions like saliva, semen, gastric juice contain blood group antigens. The individuals whose body fluids other than blood contain blood group antigens are known as secretors whereas the rest are nonsecretors. The secretor status of an individual is a genetically controlled factor. The role of genetic factors in the pathogenesis of duodena...

(This section is meant for residents to check their understanding regarding a particular topic) QUESTIONS 1. Briefly describe embryogenesis of duo-denal atresia 2. How duodenal atresia is classified? 3. What anomalies are associated with du-odenal atresia? 4. Discuss the role of antenatal ultrasound in babies with duodenal atresia 5. What are the important clinical features of duodenal atresia?...

Crohn's disease (CD) may involve any part of the gastrointestinal tract, from the mouth to the anus. Approximately >90% of cases occur in the small bowel and colon. Upper gastrointestinal involvement, especially duodenal manifestation, is relatively rare. Therefore, adequate medical treatment for duodenal CD has not yet been established. We report a case of CD with duodenal involvement. A 46-ye...

AIMS To explore the association between duodenal adenoma and carcinoma in patients with familial adenomatous polyposis (FAP). METHODS A multicentre survey of 1262 patients with FAP yielded 47 cases of duodenal cancer. The association between adenoma and cancer was assessed in these cases. RESULTS Adenomatous tissue was found within duodenal cancer in 29 of 44 (66%) patients with FAP and in ...

Duodenal ulceration is a chronic disease the causes of which remain unknown. Current medical treatment interrupts the natural history and accelerates ulcer healing. It does not cure ulcers. All duodenal ulcers are generally considered together even though pathophysiological mechanisms differ from patient to patient. It should not be surprising that some duodenal ulcer patients respond relativel...

(BGHs) are uncommon duodenal lesions, and account for approximately 5% of all duodenal masses (1). BGHs contain cysts on rare occasions, and only a very small number of cases of cystic BGH with accompanying computed tomography (CT) or magnetic resonance imaging (MRI) documentation have been reported (2-4). Imaging diagnosis of BGHs is usually a challenge, due to their nonspecific appearance. Th...

Gastric mucosal phospholipids, and in particular those of the surface layer, play an important part in mucosal barrier function. This study examined whether the phospholipid composition of the full thickness gastric mucosa is changed in peptic ulcer disease and gastritis. The phospholipid composition of gastric mucosa from endoscopic biopsy specimens in 28 subjects (eight healthy controls, 12 p...