The integration of renewable energy sources (RESs) remains growing rapidly in recent years. At the same time, security problems after contingencies were attracting great attention, due to deficiencies for stable operation, even could induce collapse integrated systems with deep interconnection such RESs. To existing issues, hyper-plane (HP) expression is proved be an excellent tool power system...

reservoir permeability is a critical parameter for characterization of the hydrocarbon reservoirs. in fact, determination of permeability is a crucial task in reserve estimation, production and development. traditional methods for permeability prediction are well log and core data analysis which are very expensive and time-consuming. well log data is an alternative approach for prediction of pe...

Blood-brain barrier opening using focused ultrasound and microbubbles has been experimentally established as a noninvasive and localized brain drug delivery technique. In this study, the permeability of the opening is assessed in the murine hippocampus after the application of focused ultrasound at three different acoustic pressures and microbubble sizes. Using dynamic contrast-enhanced MRI, th...

The robustness of controlled release formulations when co-ingested with alcohol is a current concern expressed by regulatory authorities, especially with regard to dose dumping. One such controlled release formulation commonly used is film coating composed of ethyl cellulose (EC) and hydroxypropyl cellulose (HPC). The aim of this study was to investigate how the presence of ethanol in the disso...

PURPOSE To determine whether early assessment of cerebral microvessel injury can predict late neurocognitive dysfunction after brain radiation therapy (RT). EXPERIMENTAL DESIGN Ten patients who underwent partial brain RT participated in a prospective dynamic contrast-enhanced magnetic resonance imaging (MRI) study. Dynamic contrast-enhanced MRI was acquired prior to, at weeks 3 and 6 during, ...

Hydrologic responses to earthquakes, including liquefaction, changes in stream and spring discharge, changes in the properties of groundwater such as geochemistry, temperature and turbidity, changes in the water level in wells, and the eruption of mud volcanoes, have been documented for thousands of years. Except for some water-level changes in the near field which can be explained by poroelast...

One the one hand, capillary permeability to water is a well-defined concept in microvascular physiology, and linearly relates the net convective or diffusive mass fluxes (by unit area) to the differences in pressure or concentration, respectively, that drive them through the vessel wall. On the other hand, the permeability coefficient is a central parameter introduced when modeling diffusible t...

Lithium at serum concentrations up to 1 mmol/L has been used in patients suffering from bipolar disorder for decades and has recently been shown to reduce the risk for ischemic stroke in these patients. The risk for stroke and thromboembolism depend not only on cerebral but also on general endothelial function and health; the entire endothelium as an organ is therefore pathophysiologically rele...

Interstitial collagen formation and transformation of the fenestrated hepatic sinusoids into continuous capillaries are major ultrastructural changes that occur in liver cirrhosis and fibrosis. These modifications lead to progressive restriction of blood-liver exchanges. The purpose of our study was to evaluate the permeability changes in a model of hepatic fibrosis by using dynamic computed to...

A dynamic contrast enhanced (DCE) approach for tumor photoacoustic (PA) imaging is described. Novel water soluble melanin-based derivatives are synthesized that exhibit good PA properties, stability, safety and accumulation in tumor bearing mice. This melanin derivative is capable to characterize tumor vasculature and to monitor vessel permeability changes upon antiangiogenic treatment. DCE-PA ...