Oppositional defiant disorder (ODD) is a common and impairing characterized by angry/irritable mood, argumentative/defiant behavior, vindictiveness. These symptom domains are related to predict attention-deficit/hyperactivity disorder, conduct mood anxiety problems. ODD often begins early during preschool, relatively stable, exhibits irritability as core feature. also associated with other disr...

BACKGROUND This article presents prospective lower bound estimations of findings on prevalence, incidence, clinical correlates, severity markers, co-morbidity and course stability of threshold and subthreshold recurrent brief depressive disorder (RBD) and other mood disorders in a community sample of 3021 adolescents. METHOD Data were collected at baseline (age 14-17) and at two follow-up int...

BACKGROUND Recent studies support a distinction between acute and chronic forms of depression, which contrasts the single-disease hypothesis for depressive disorders. Insight into the (determinants of) the 3-year naturalistic course of major depressive disorder (MDD), dysthymic disorder (Dysth) and double depression (DD) may contribute to this debate. METHODS Data were derived from NEMESIS, a...

OBJECTIVE To investigate the association between mental disorders and cigarette use and nicotine dependence among pregnant women in the United States. METHODS A face-to-face general population survey was conducted on participants in the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions. One thousand five hundred sixteen women reporting a pregnancy in the past year were...

BACKGROUND Although several studies have shown that life adversities play an important role in the etiology and maintenance of both depressive and anxiety disorders, little is known about the relative specificity of several types of life adversities to different forms of depressive and anxiety disorder and the concurrent role of neuroticism. Few studies have investigated whether clustering of l...

Personality traits are important candidate predictors of suicidal behavior. Several studies have reported an association between personality/temperament traits and suicidal behavior, suggesting personality traits as intermediary phenotypes related to suicidal behavior. Thus, it is possible that suicide attempts can be accounted for by increased familial rates of risk personality traits. The aim...

BACKGROUND Self-stigma is a maladaptive psychosocial phenomenon that can affect many areas of patients' lives and have a negative impact on their quality of life (QoL). This study explored the association between self-stigma, QoL, demographic data, and the severity of symptoms in patients with depressive disorder. PATIENTS AND METHODS Patients who met the International Classification of Disea...

CONTEXT Literature is inconsistent about the role of gender in mediating the relationship between life events and depression. AIM Our objective was to explore gender differences in patterns and frequencies of stressful life events before onset of a depressive episode. SETTING AND DESIGN Cross-sectional study at a tertiary care center. SUBJECTS AND METHODS One hundred patients fulfilling D...

OBJECTIVE Offspring of bipolar parents have a genetically increased risk of developing mood disorders. In a longitudinal study, the authors followed a bipolar offspring cohort from adolescence into adulthood to determine the onset, prevalence, and early course of mood disorders and other psychopathology. METHOD The Dutch bipolar offspring cohort is a fixed cohort initiated in 1997 (N=140; age...

OBJECTIVE Comorbid bipolar and panic disorders aggregate in families. A phenotypic trait shared by both disorders is the sudden shift in affect observed in panic attacks and some rapid cycling states. The authors investigated whether comorbidity of bipolar disorder and panic disorder is associated with rapid mood switching in families with a high rate of bipolar disorder. METHOD Six hundred s...