INTRODUCTION Acute rejection (AR) is a major determinant of renal allograft survival. The incorporation of new immunosuppressive agents explains the improvement seen in the results of transplantation in recent years. OBJECTIVE To assess the optimal immunosuppression regimen according to the immunological risk of renal transplant patients. METHOD We performed a retrospective study of 977 con...

INTRODUCTION Tympanometry is currently the most frequently used tool for assessing the status of the middle ear, commonly assessed using a single 226Hz tone. However, the use of the Acoustic Immittance Measures with a wideband stimulus is a promising high-resolution evaluation, especially in individuals known to have middle ear alterations, such as Down syndrome patients. OBJECTIVE The aim of...

The Kir4.1 gene (KCNJ10) encodes an inwardly rectifying K(+) channel subunit abundantly expressed in the CNS. Its expression in the mammalian inner ear has been suggested but its function in vivo in the inner ear is unknown. Because diverse human hereditary deafness syndromes are associated with mutations in K(+) channels, we examined auditory function and inner ear structure in mice with a gen...

The octave illusion is produced by a dichotic sequence of tones that alternate in frequency between 400 and 800 Hz, such that when the right ear receives 400 Hz the left ear receives 800 Hz; and vice versa. Most listeners obtain the illusion of a single high tone in one ear alternating with a single low tone in the other ear. Further, most right-handers hear the high tone on the right and low t...

More than democratic deficit, most countries of the Middle East suffer from the fundamental problem over their national identity. More than three-quarters of a century after the disintegration of the Ottoman Empire from which most of them emerged, these states have been unable to define, project, and maintain a national identity that is both inclusive and representative. None of the countries o...

OBJECTIVE The aim of this study was to determine tympanometric values of children who attend Oporto daycare centers and further analyze any relations with host and environmental factors. METHODS Cross sectional study in a randomly selected sample of 117 daycare children up-to 3-years old from Oporto. Tympanometric measures were collected. RESULTS Children presented in left ear (LE) a mean p...

introduction: chronic otitis media (com), a persistent and durable inflammation and infection of the middle ear, is a common disorder. alterations in the contralateral ear in sufferers have been observed in recent years. because only a few studies have been reported in this area, we performed this study in order to assess alterations in the contralateral ear of patients with com.   materials an...