Background: Sepsis is a major cause of mortality in neonatal. Diagnosing neonatal sepsis challenge, as its clinical symptoms are not specific. Various studies have been conducted to identify infection markers for early identification sepsis, but none shown satisfactory results. Therefore, we aimed determine the validity eosinophil count and monocyte lymphocyte ratio (MLR) detection sepsis. Obje...

Original Article Neonatal sepsis Community acquired neonatal sepsis Blood culture Serum CRP. Objectives: 1)To study the causative organisms and profile of sepsis in outborn newborns admitted to NICU in a rural hospital.2)To study the usefulness of S.CRP as a tool in rural and resource limited settings for diagnosis of Early and Late onset sepsis as well as in suspected & proven sepsis cases. Se...

Neonatal sepsis is a leading cause of neonatal mortality. Congenital heart disease accounts for additional risk of sepsis in neonates. Here we report a case of Down's syndrome with late onset neonatal sepsis associated with multiple superficial skin abscesses simulating staphylococcal infection. The baby was empirically treated with vancomycin. Subsequently, multidrug resistant Klebsiella pneum...

OBJECTIVE To assess different perinatal findings and sample collection timing in newborns with early-onset sepsis comparing those with low IL-6 levels to the ones with high levels. METHODS Eighty-five newborn infants, with clinical signs of sepsis and/or positive blood cultures, had plasma IL-6 collected in the initial evaluation for early-onset sepsis in the first 96 hours of life. They were...

OBJECTIVE To perform a decision analysis to understand better the implications of 19 potential group B streptococcus screening and treatment strategies. METHODS We searched the literature to locate appropriate articles from which to derive probability estimates. Using decision analysis, we determined the likely outcomes of 19 group B streptococcus screening and treatment strategies and focuse...

espite the known efficacy of the intrapartum antibiotic prohylaxis (IAP),1 no Group B Streptococcus (GBS) prophylaxis rogram are in place in Brazil,2 and rates of early-onset sepsis EOS) may be underestimated. We conducted a retrospective nalysis on the incidence EOS, IAP use and outcomes of infants orn in a Brazilian University Hospital (Hospital de Clínicas e Uberlândia, HC-U). An early-onset...

INTRODUCTION Neonatal mortality in developing countries is usually due to an infectious cause. The gold standard of investigation in developing countries is a positive blood culture. It is important to know the aetiology of neonatal bloodstream infections so that empiric treatment can be effective. METHODOLOGY We conducted a retrospective clinical audit over ten years between January 2000 unt...