La enfermedad de células falciformes (ECF) es una hemoglobinopatía herencia autosómica recesiva. prevalencia ECF puede cambiar especialmente por fenómenos migratorios. Objetivo: Describir las características pacientes con ECF, al diagnóstico, en un hospital referencia a lo largo década. Pacientes y Método: Estudio retrospectivo clínicas laboratorio menores 15 años diagnosticados el Servicio Onc...

The dual toxicity/essentiality of copper forces cells to maintain a tightly regulated homeostasis for this metal in all living organisms, from bacteria to humans. Consequently, many genes have previously been reported to participate in copper detoxification in bacteria. Myxococcus xanthus, a prokaryote, encodes many proteins involved in copper homeostasis that are differentially regulated by th...

Abstract This paper investigates strategic entrepreneurial choice between the UK Big 3 platforms–Crowdcube, Seedrs and SyndicateRoom–that exemplify three main equity crowdfunding (ECF) shareholder structures identified in literature. ECF has become a for both entrepreneurs angel venture capital funds as it offers mutually beneficial advantages to both, especially under co-investment model where...

During the past decade, equity crowdfunding (ECF) has emerged as an alternative funding channel for startup firms. In Germany, Small Investor Protection Act became binding in July 2015, with legislative goal to protect investors engaging this new asset class. Since then, pledging more than 1,000 EUR now must self-report their income and wealth. Investing 10,000 a single ECF issuer is only possi...