OBJECTIVE To determine the sequelae of neonatal seizures in a cohort of newborns, recruited over a six month period. DESIGN Prospective hospital based study. SETTING The neonatal intensive care unit (NICU) of a tertiary care hospital. PARTICIPANTS 135 babies were recruited of whom 10 died and 25 were lost to follow up. METHODS The cases were followed up over four months. RESULTS 68% o...

OBJECTIVE This study tested the hypothesis that frontal error negative wave amplitude on EEG during Stroop test activation predict change in depressive symptoms in depressed elders. METHOD Twenty-two older patients with major depression received controlled treatment with citalopram at a target dose of 40 mg/day for 6 weeks. Paramedian error negative waves were recorded during Stroop activatio...

Focal electromagnetic slow-wave activity is generated in the vicinity of brain lesions. The present study confirmed this for the EEG delta band (1-4 Hz): Activity in the waking state was pronounced over the hemisphere of the lesion in 11 stroke patients suffering from aphasia, but not in 10 healthy controls. Changes of abnormal slow waves patterns were tracked from 1-3 months to 2 years poststr...

Children with ASD often suffer from epilepsy and paroxysmal EEG abnormality. Purposes of this study are the confirmation of incidence of epileptic seizures and EEG abnormalities in children with autism using a high performance digital EEG, to examine the nature of EEG abnormalities such as locus or modality, and to determine if the development of children with ASD, who have experienced developm...

INTRODUCTION Whole head magnetoencephalography (MEG) systems facilitate simultaneous recording from the entire brain surface and deep structures. Thus MEG may be accepted as a clinically feasible method for the evaluation of epileptic patients not diagnosed with EEG. CLINICAL CASE A 11 year old female, with tonic generalized seizures since birth. At the present time, seizures consist of initi...

Electroencephalography (EEG) recordings of rhythm perception might contain enough information to distinguish different rhythm types/genres or even identify the rhythms themselves. In this paper, we present first classification results using deep learning techniques on EEG data recorded within a rhythm perception study in Kigali, Rwanda. We tested 13 adults, mean age 21, who performed three beha...

Macroscopic electroencephalographic (EEG) fields can be an explicit top-down neocortical mechanism that directly drives bottom-up processes that describe memory, attention, and other neuronal processes. The top-down mechanism considered is macrocolumnar EEG firings in neocortex, as described by a statistical mechanics of neocortical interactions (SMNI), developed as a magnetic vector potential ...

In this study a pharmacokinetic-pharmacodynamic model is proposed for drugs with nonlinear elimination kinetics. We applied such an integrated approach to characterize the pharmacokinetic-pharmacodynamic relationship of phenytoin. In parallel, the anticonvulsant effect and the electroencephalogram (EEG) effect were used to determine the pharmacodynamics. Male Wistar-derived rats received a sing...