A multi-stimuli responsive pseudo [3]rotaxane NI-DBC/RB-DBA was composed of a green-emissive (λem = 530 nm) naphthalimide-based macrocyclic host and turn-on red-emissive 595 rhodamine-based guest towards Fe3+ ion, which illustrated interesting photo-physical properties in dioxane/H2O (4:6, v/v) solutions. Due to the chelation-induced ring unfolded form rhodamine unit upon addition mono-fluoroph...

background in many industries, noise is attributed as the most prevalent harmful agent threatening workers' health. geographic information system (gis) is an applicable surveying tool in civil engineering. but, the use of gis for noise and hearing loss screening seems to be partly a new approach. objectives this study aimed to apply gis in noise and hearing loss screening in the production hall...

Immobilization causes rapid and massive bone loss. By comparing Botulinum Toxin A (BTX)-induced bone loss in mouse strains with different genetic backgrounds we investigated whether the genetic background had an influence on the severity of the osteopenia. Secondly, we investigated whether BTX had systemic effects on bone. Female mice from four inbred mouse strains (BALB/cJ, C57BL/6 J, DBA/2 J,...

Background Recently, an angiotensin-converting enzyme inhibitor was shown to have a beneficial effect on virusinduced myocardial injury. We investigated the effect of a new angiotensin II type 1 receptor antagonist, (+)-1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate (TCV-116), in an animal model of viral myocarditis induc...

Dibromoacetic acid (DBA) and bromochloroacetic acid (BCA) are prevalent disinfection by-products of drinking water that produce defects in spermatogenesis and fertility in adult rats. Previously we demonstrated that BCA compromises the fertility of cauda epididymal rat sperm and SP22, a sperm membrane protein that is highly correlated with the fertility of these sperm. Herein, we administered D...

The HINT provides an efficient and reliable method of assessing speech intelligibility in quiet and in noise by using an adaptive strategy to measure speech reception thresholds for sentences, thus avoiding ceiling and floor effects that plague traditional measures performed at fixed presentation levels A strong need for such a test within the Canadian Francophone population, led us to develop ...

We have used the murine model of aerosol-induced experimental tuberculosis to assess the effects of four clinical isolates and a reference strain of Mycobacterium tuberculosis on resistant C57BL/6 mice and susceptible DBA/2 mice. Histological studies and detection of 25 cytokines potentially involved in the infection were carried out. DBA/2 mice showed higher concentrations of bacilli in bronch...

Hair color stereotyping is well documented in jokes and the psychological literature. Blondes are stereotyped as incompetent, but likeable, while redheads are seen as competent but cold, or often with a fiery temper. Do these stereotypes affect job progression, mobility, and the rise to the corporate suite? To test this question, the hair color of CEOs of the top 500 members of the London Finan...

Duchenne muscular dystrophy, one of the most common lethal genetic disorders, is caused by mutations in the DMD gene and a lack of dystrophin protein. In most DMD patients and animal models, sporadic dystrophin-positive muscle fibres, called revertant fibres (RFs), are observed in otherwise dystrophin-negative backgrounds. RFs are thought to arise from skeletal muscle precursor cells and clonal...

Dibromoacetic acid (DBA) is a drinking water disinfection by-product. Its analogs, dichloroacetic acid (DCA) and trichloroacetic acid (TCA), are liver carcinogens in rodents. We evaluated the ability of DBA to cause DNA hypomethylation, glycogen accumulation, and peroxisome proliferation that are activities previously reported for the two other haloacetic acids. Female B6C3F1 mice and male Fisc...