Treatment of quiescent primary human fibroblasts with tumor necrosis factor (TNF) alpha, TNF-beta, interleukin-1, interferon (IFN) alpha, IFN beta, or IFN gamma induced Egr-1 mRNA. In primary human fibroblasts TNF-alpha and TNF-beta were mildly mitogenic and IFN alpha and IFN gamma were growth inhibitory. However, in HeLa cells TNF but not IFN induced the expression of Egr-1 mRNA, while both cy...

Early Growth response-1 (Egr-1) is a transcription factor that possesses a variety of biological functions. It has been shown to regulate HSV-1 gene expression and replication in different cellular environments through the recruitment of distinct cofactor complexes. Previous studies demonstrated that Egr-1 can be induced by HSV-1 infection in corneal cells but the level was lower compared to ot...

Early growth response factor-1 (Egr-1) controls the expression of a growing number of genes involved in the pathogenesis of atherosclerosis and postangioplasty restenosis. Egr-1 is activated by diverse proatherogenic stimuli. As such, this transcription factor represents a key molecular target in efforts to control vascular lesion formation in humans. In this study, we have generated DNAzymes t...

in the diesel engine exhaust gas recirculation (egr) components, valve and connecting pipes are the critical components and fails often during new engine development. these components are important for meeting nox emissions norms. therefore design of these components should remain robust. but the challenge in design is compact packaging of complete egr components on the engine consequently vibr...

in this study a heat exchanger is designed for cooling exhaust gas and an experiment is carried out to investigate the effect of exhaust gas recirculation (egr) temperature on destruction of the fuel’s availability due to combustion processes in idi diesel engine cylinder. to serve this aim an exergy analysis is conducted on the engine cylinder which provides all the availability terms by which...

زمینه و هدف: کم‌تحرکی در مقابل آن تمرین جزء عوامل مرتبط با شاخص‌های آسیب کبدی به‌شمار می‌روند. وجود این هنوز نقش بسیاری از تمرین‌های ورزشی به‌ویژه تمرینات تناوبی مقاومتی مصرف برخی مکمل‌های غذایی جمله اسپیرولینا بر ایمنی التهابی کاملاٌ شناخته نشده است؛ بنابراین هدف پژوهش تعیین اثر هشت هفته مکمل‌دهی هوازی فعالیت بافت کبد بیان ژن CXCL1 عضلة موش‌های صحرایی نر بود.مواد روش‌ها: نیمه‌تجربی، 60 سر موش ن...

هديکچ ت یحارط یارب ديدج شور کي هلاقم نيا رد تيوق ارا یطخ زاف اب هدرتسگ هدننک ئ يم ه دوش . شور نيا تيوقت و لاسروسنارت لاتيجيد رتليف یژولوپوت نيب تهابش یانبم رب يم هدرتسگ هدننک دشاب . نيا یانبم رب رواجم هقبط ود نيب ريخات رادقم و هدننک تيوقت زا هقبط ره نيگ یژولوپوت رتليف هيروف طسب زا هدافتسا اب Raise Cosine يم نييعت یروط یسناکرف هلصاف رد هک دوش 0-40 GHz تيوقت یطخ زاف هصخشم یاراد هدننک دشاب ه...

* لوئســ م هدنســ يون : ،نارــ هت ناــ بايخ ،رســ نارهت ناــ بايخ رسنارهت ميرك هاگنامرد ،رفولين راولب ،بيغتسد نفلت : 44506655 email: [email protected] فده و هنيمز : اب نمزم سامت تارثا لاّلح اه ناسنا تملاس رب يلآ ي هـتفرگ رارـق يسررب دروم فلتخم تاعلاطم رد اه اب سامت نيب هجوت لباق طابترا رگناشن هك لاّلح اه تيرفنولورمولگ و تسا هدوب اه . ركراـم يسررب هعلاطم نيا زا فده يويلك تيمس هب ساسح يرا...

Banks, Mark F., Evgenia V. Gerasimovskaya, Doug A. Tucker, Maria G. Frid, Todd C. Carpenter, and Kurt R. Stenmark. Egr-1 antisense oligonucleotides inhibit hypoxia-induced proliferation of pulmonary artery adventitial fibroblasts. J Appl Physiol 98: 732–738, 2005. First published October 8, 2004; doi:10.1152/japplphysiol. 00821.2004.—In most mammalian species, chronic exposure to hypoxia leads ...