Background: Reviews of the epidemiology of Huntington’s disease (HD) suggest that its worldwide prevalence varies widely. This review was undertaken to confirm these observations, to assess the extent to which differences in caseascertainment and/or diagnosis might be responsible, and to investigate whether the prevalence pattern has changed over the past 50 years. Methods: Eighty two relevant ...

The CHI3L1 gene has been widely regarded as a genetic candidate for asthma. Since the identification of functional polymorphism, CHI3L1 gene -131C/G (rs4950928), numbers of studies have been performed to estimate the relationship between it and asthma, but the results remain inconclusive. The present meta-analysis was conducted to evaluate the real association of CHI3L1 C-131G polymorphism on r...

Purpose: There is common consensus that cancer and its treatment can impair the body, but combined evidence of the previous literature in cancer survivors is missing. Therefore, we reviewed body image in cancer survivors and focused on case‐control studies, in order to draw conclusions as to whether body image might be altered due to cancer. Methods: Medline, Cinahl, Embase, and PsycInfo were s...

Sources and dates of last search: Ovid MEDLINE (R) <1950 to May week 3 2008> Pubmed/Medline – April 16/08; CT – 48 hits/22 for initial review of abstract; MRI 47 hits/ 34 for review; Nuclear – 42 hits/ 5 for review; ECHO – 162 hits/47 for review EMBASE – May 13/08 – CT – 27 hits7 for review; MRI – 31 hits 1; Nuclear – 7; ECHO – 194 hits -5 Manual search of references May 16/08 – CT – 2; MRI – 1...

Methods In this systematic review and meta-analysis, we analysed published and unpublished population-based data for the causes of vision impairment and blindness from 1980 to 2014. We identified population-based studies published before July 8, 2014, by searching online databases with no language restrictions (MEDLINE from Jan 1, 1946, and Embase from Jan 1, 1974, and the WHO Library Database)...

Background: Reviews of the epidemiology of Huntington’s disease (HD) suggest that its worldwide prevalence varies widely. This review was undertaken to confirm these observations, to assess the extent to which differences in caseascertainment and/or diagnosis might be responsible, and to investigate whether the prevalence pattern has changed over the past 50 years. Methods: Eighty two relevant ...

Background: Patient misidentification, as a major patient safety issue, occurs in any healthcare setting and leads to inappropriate medical procedures, diagnosis or treatment, with serious outcomes. Objectives: The study aimed to investigate the effectiveness of wristband bar-code medication scanning to reduce medical errors (ME). Methods: A meta-analysis study was conducted. The relevant studi...

Background: Preeclampsia, whose causes remain unknown, is a multifaceted syndrome suffered by pregnant women world-wide. Objectives: This study is to quantitatively analyze the association between exposure to intrauterine devices (IUDs) and risks of developing preeclampsia during pregnancy. Search strategy: Literature search was performed on Pubmed, Medline, EMBASE and COHRANE Library. Both mes...

• Objective: To evaluate the available evidence supporting the use of albumin for diagnosis and treatment of hepatorenal syndrome (HRS). • Methods: We searched MEDLINE, EMBASE, and the Cochrane Library for articles published in English between 1966 and March 2013. To evaluate the role of albumin in the diagnosis of HRS, we looked for trials comparing albumin to other plasma expanders. To evalua...

Methods A systematic literature search of MEDLINE, EMBASE and Cochrane CENTRAL was conducted for randomized controlled trials evaluating oral anti-diabetic drugs in patients at high risk for developing Type 2 diabetes. Mixed-treatment comparison meta-analysis methods were used to evaluate the relative risks and risk differences of developing Type 2 diabetes, along with associated 95% credible i...