Substrate-mediated gene delivery is a promising method due to its unique ability to preconcentrate exogenous genes onto designated substrates. However, many challenges remain to enable continuous and multiround delivery of the gene using the same substrates without depositing payloads and immobilizing cells in each round of delivery. Herein we introduce a gene delivery system, nanosubstrate-med...

Abstract With promising applications in medical diagnosis and therapy, the behavior of shell-encapsula-ted ultrasound contrast agents (UCAs) has attracted considerable attention. Currently, second-generation stabilized by a phospholipid membrane are widely used studies have focused on dynamics single shell-encapsulated microbubbles. To improve safety efficiency methods using propagation or targ...

Oxovanadium(IV), manganese(II) and copper(II) complexes of a Schiff base ligand derived from 2,4-dihydroxyacetophenone and 1,2-diaminocyclohexane have been encapsulated in the nanocavity of zeolite-Y by flexible ligand method and characterized by metal analysis, IR spectroscopic studies and X-ray diffraction patterns. The encapsulated complexes abbreviated here as CuL-Y, MnL-Y and VOL-Y catalyz...

We extend research on fundamental accounting signals (signals) to a quarterly context and investigate the relative efficiency of analysts and whisperers in using signals in generating onequarter-ahead EPS forecasts. We find (1) a subset of signals found to be relevant in predicting one-year-ahead EPS changes are also relevant in predicting one-quarter-ahead EPS changes, (2) neither analysts nor...

While a vast amount of editorial metadata is being actively gathered and used by music collectors and enthusiasts, it is often neglected by music information retrieval and musicology researchers. In this paper we propose to explore Discogs, one of the largest databases of such data available in the public domain. Our main goal is to show how largescale analysis of its editorial metadata can rai...

In recent years, the discovery of many non-encapsulated isolates of Trichinella, designated Trichinella pseudospiralis and the identification of a new non-encapsulated species, Trichinella papuae, has revealed that the biomass of the genus Trichinella does not only include the well known encapsulated species (T. spiralis, T. nativa, T. britovi, T. murrelli, and T. nelsoni) but also includes geo...

Quality of minced silver carp (Hypophthalmicthysmolitrix) with gum arabic encapsulated with 1 and 1.5%( w/w) and rosemary extract (RE) (1 and 1.5% w/w) stored at 4˚C was studied chemically (peroxide value and total volatile nitrogen) and microbiologically (total viable count, psychrotrophic count) analyses. The efficacy of the encapsulated extract to control the population of Esche...

The current methods for treatment of cancers are inadequate and more specific methods such as gene therapy are in progress. Among different vehicles, cationic liposomes are frequently used for delivery of genetic material. This investigation aims to prepare and optimize DOTAP cationic liposomes containing an antisense oligonuclotide (AsODN) against protein kinase C alpha in non-small cells lung...

Abstract There is a growing interest in co-encapsulating multiple species to harness potential synergy between them, enhance their stability and efficacy various products. The aim of this work was co-encapsulate vitamin D 3 rutin inside chitosan-zein microparticles using simple easily scalable process for food fortification. This achieved via anti-solvent precipitation coupled with spray-drying...