Background: Encapsulating peritoneal sclerosis related to long-term peritoneal dialysis is a serious and complicated clinical dilemma and surgical treatment might be the final therapeutic option when bowel obstruction occurred. However, the operative therapy comprising peritonectomy and enterolysis is a complex and risky procedure, and the surgical mortality is mainly related to the iatrogenic ...

Inflammation, fibrosis, and angiogenesis underlie the pathophysiology of encapsulating peritoneal sclerosis (EPS). The irreversible sclerosis of visceral and parietal peritoneum that characterizes EPS can be seen in peritoneal dialysis (PD) patients after long periods on dialysis. Peroxisome proliferator-activated receptors (PPARs) are the major regulator of key metabolic pathways of various in...

Encapsulating peritoneal sclerosis (EPS) is a rare complication of dialysis which mortality can reach 50%. The usual treatment involves suspension the technique, medical treatment, and surgical enterolysis. We report case 36-year-old female who undergone continuous ambulatory without complications for 10 years. She presented at emergency department with abdominal pain diagnosis peritonitis was ...

BACKGROUND Sclerosing peritonitis (SP) and encapsulating peritoneal sclerosis (EPS) are serious complications of continuous ambulatory peritoneal dialysis. Although we have shown previously that matrix metalloproteinase-2 (MMP-2) is increased in peritoneal injury leading to SP/EPS, most of the MMP-2 in the dialysate drained from the peritoneal cavity was the latent form that was lacking activit...

Peritoneal dialysis (PD) is a common treatment for patients with reduced or absent renal function. Long-term PD leads to peritoneal injury with structural changes and functional decline. At worst, peritoneal injury leads to encapsulating peritoneal sclerosis (EPS), which is a serious complication of PD. In order to carry out PD safely, it is important to define the mechanism of progression of p...