نتایج جستجو برای: endocannabinoid signaling

تعداد نتایج: 301155  

Journal: :Neuron 2003
Tamás F. Freund Norbert Hájos

Previous work has suggested a role for retrograde synaptic signaling via endogenous cannabinoids in regulating the inhibitory control of neuronal activity. In this issue of Neuron, Chevaleyre and Castillo provide evidence for another form of endocannabinoid-mediated depression of hippocampal inhibition, which is activity dependent and long lasting.

Journal: :The Journal of biological chemistry 2010
Shuxian Jiang Radoslaw Zagozdzon Meritxell Alberich Jorda Kalindi Parmar Yigong Fu John S Williams Jodi Anne T Wood Alexandros Makriyannis Naheed Banu Shalom Avraham Jerome E Groopman Hava Karsenty Avraham

Endocannabinoids are lipid signaling molecules that act via G-coupled receptors, CB(1) and CB(2). The endocannabinoid system is capable of activation of distinct signaling pathways on demand in response to pathogenic events or stimuli, hereby enhancing cell survival and promoting tissue repair. However, the role of endocannabinoids in hematopoietic stem and progenitor cells (HSPCs) and their in...

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