Objective: The study aims to investigate the prognostic factors in uterine endometrioid adenocarcinoma that affect survival outcomes. 
 Materials and Methods: This retrospective includes 144 cases which underwent surgical treatment for adenocarcinoma. Demographic data tumour characteristics were evaluated lymph node metastasis. Stage I grade 1-2 tumours divided into lymphadenectomy non-lym...

background : endometrial cancer is the most common type of malignancy in female reproductive system and is the fourth common cancer after breast, lungs and colorectal cancers. our aim is to report epidemiology and frequency types of endometrial cancer and clinical staging and grading of this disease. methods : in this description and cross-sectional study, 75 patients with diagnosed endometrial...

results the mean age at the time of diagnosis was 54 years (range, 28 - 74). cause-specific survival rates of the entire group were 92%, 87% and 82%, at two, three and five years, respectively. the five-year cause-specific survival rates for grades one, two and three were 98%, 88% and 68%, respectively. multivariate analysis revealed that age, depth of myometrial invasion, involvement of ovarie...

Endometriosis is a common gynecological disease in which tissue sim ilar to the endometrium proliferates at sites outside the uterine cavity. Malignant transformation of endometriosis to endometrioid and clear cell ovarian carcinomas has been documented in histolÃ3gica!studies, but no molecular genetic evidence exists to support that endometriosis is the clonal precursor of such malignancies. W...

Introduction. LeFort colpocleisis (LFC) is a safe and effective obliterative surgical option for older women with advanced pelvic organ prolapse who no longer desire coital activity. A major disadvantage is the limited ability to evaluate for post-LFC gynecologic malignancies. Methods. We present the first case of endometrioid ovarian cancer diagnosed after LFC and review all reported gynecolog...

Atypical endometriosis is reported to possess a precancerous potential attributed to premalignant changes characterized by cytological atypia and architecture proliferation. Moreover, the coexistence of atypical endometriosis and neoplasms had been reported. However, cases of atypical endometriosis transformation to carcinoma are rarely reported. We describe the case of a 33-year-old woman who ...

Metabolomics, an essential technique in precision medicine, contributes to the molecular fingerprinting of tumours, further helping to understand their pathogenesis. In this work, using a LC-ESI-QTOF-MS/MS platform, we demonstrated the existence of a specific metabolomic signature which could define endometrioid endometrial carcinoma (EEC), arising the endocannabinoid system as a potential path...

Malignant transformation of endometriosis is rare and is usually seen in ovarian endometriosis. The colon and rectum are the most common sites for extragonadal endometriosis, and although serosal involvement is commonly seen, mucosal involvement is rare. Malignant transformation of endometriosis is a rare but a well-known complication of endometriosis. We report an unusual presentation of endom...

Appendiceal mucocele is a rare clinical entity, which is however quite often associated with mucinous ovarian tumor. The coexistence of mucinous cystadenoma of the appendix and endometrial adenocarcinoma has not been reported before. A 49-year-old woman presented to our clinic with postmenopausal bleeding and no other symptom. Endometrial biopsy revealed endometrial adenocarcinoma of endometrio...