IMPORTANCE Laser ablation is a rapid and minimally invasive approach for the treatment of superficial skin cancers, but efficacy and reliability vary owing to lack of histologic margin control. High-resolution reflectance confocal microscopy (RCM) may offer a means for examining margins directly on the patient. OBSERVATIONS We report successful elimination of superficial and early nodular bas...

PURPOSE The point of interest of this retrospective case review is to study refractive changes caused by the hinged lamellar keratotomy and the refractive outcome after laser ablation in a second step within the scope of laser in situ keratomileusis (LASIK) in patients with penetrating keratoplasty. METHODS Data from eight patients obtained before lamellar keratotomy, before laser ablation, a...

PURPOSE The femtosecond laser has been realized as an advantageous tool for micromachining, and the feasibility of employing it for surgical procedures has been investigated. A prior study demonstrated dose-dependent femtosecond laser photodisruption of peripheral corneal tissue through a gonioscopic lens in enucleated porcine eyes and of the trabecular meshwork (TM) in human corneoscleral rim ...

This paper presents a novel approach to the robust design of deflection actions for Near Earth Objects (NEO). In particular, the case of deflection by means of Solar-pumped Laser ablation is studied here in detail. The basic idea behind Laser ablation is that of inducing a sublimation of the NEO surface, which produces a low thrust thereby slowly deviating the asteroid from its initial Earth th...

INTRODUCTION There are various treatment modalities to remove the black patches of melanin pigmentation. The aim of the study is to clinically compare the diode laser ablation and surgical stripping technique for gingival depigmentation and to evaluate their effect on the histological changes in melanocyte activity. MATERIALS AND METHODS A total of 40 sites of 20 patients with bilateral melan...

In this paper, we establish connections between the thresholds and mechanisms of the damage and white-light generation upon femtosecond laser irradiation of wide-bandgap transparent materials. On the example of Corning Willow glass, evolution of ablation craters, their quality, and white-light emission were studied experimentally for 130-fs, 800-nm laser pulses. The experimental results indicat...

BACKGROUND Laser ablation with a neodymium-doped yttrium aluminum garnet (Nd:YAG) laser is a minimally invasive approach which is able to achieve a precise tissue necrosis. The study was aimed to assess the feasibility and efficiency of laser ablation in the treatment of retroperitoneal and hepatic portal unresectable metastatic lymph nodes. METHODS Eight patients including 11 pathologically ...

Recent applications of the breathing sphere model for molecular dynamics simulations of laser ablation of organic solids have yielded detailed microscopic data of the processes involved. The results to date include a prediction of a fluence threshold for ablation, an explanation for the presence of clusters in the plume and a consistent analytical description of the velocity distribution for bo...

Flat and spherical PMMA surfaces were ablated with a standard refractive surgery laser system. The ratio of profiles on flat to spherical PMMA surfaces was used to estimate experimentally the radial change in ablation efficiency for PMMA and cornea. Changes in ablation efficiency accounted for most of the asphericity increase found clinically, using the same laser system. This protocol is usefu...