The Research and De®elopment Pipeline management problem has far-reaching economic implications for new-product-de®elopment-dri®en industries, such as pharmaceutical, biotechnology and agrochemical industries. Effecti®e decision-making is required with respect to portfolio selection and project task scheduling in the face of significant uncertainty and an e®er-constrained resource pool. The her...

We have characterized cis-acting elements that direct the early phase of Hoxc-8 expression using reporter gene analysis in transgenic mice. By deletion we show that a 135 bp DNA fragment, located approximately 3 kb upstream of the coding region of Hoxc-8, is capable of directing posterior neural tube expression. This early neural tube (ENT) enhancer consists of four separate elements, designate...

We will be presenting two theorems in this paper. The first theorem, which is a new result, is about the non-existence of integer solutions of the cubic diophantine equation. In the proof of this theorem we have used some known results from theory of binary cubic forms and the method of infinite descent, which are well understood in the purview of Elementary Number Theory(ENT). In the second th...

The incubation of 15beta-hydroxy-3-oxo-ent-kaur-16-ene (1) with the fungus Gibberella fujikuroi afforded 11beta-hydroxy-3,15-dioxo-ent-kaurane (6), 11beta,15beta-dihydroxy-3-oxo-ent-kaur-16-ene (8), 7beta,11beta,15beta-trihydroxy-3-oxo-ent-kaur-16-ene (9), 7alpha,11beta-dihydroxy-3,15-dioxo-ent-kaurane (7), and 7alpha,11beta,15beta-trihydroxy-3-oxo-ent-kaur-16-ene (10). The incubation of 15beta...

SMC students re affirm ed the election of Kathy Barlow and Misssy U nderm an for student body p re s id e n t an d v icepresident in F rid ay ’s balloting at St. M ary’s . In the election held to clarify a nine vote discrepancy which was discorded in the first totals, Barlow and U nderm an collected 606 votes to defeat Jan e Sheehy and Sue Welte who polled 491 votes. P leased with the large tur...

صخلملا Infertility affects 15% of couples seeking children worldwide and male factor is evident in about 30-50% of the cases. To assess the effect of sperm chromatin integrity on the outcomes of intracytoplasmic injection, sperm DNA compactness was evaluated by acridine orange staining in 40 fertile and 44 infertile men attending one infertility clinic. The results showed no significant differe...

صخلملا The search for novel anticancer drugs continues. This work includes a preliminary study of the effect of two crude extracts of Greek or Mediterranean sage (Salvia triloba L. f.) on three malignant human cell lines and one malignant murine cell line. A boiling water extract and a methanolic extract were prepared from dried leaves of S. triloba. Yields of extraction were 9.8 and 22.4%, res...

Lukashkin, Andrei N., Victoria A. Lukashkina, P. Kevin Legan, Guy P. Richardson, and Ian J. Russell. Role of the tectorial membrane revealed by otoacoustic emissions recorded from wild-type and transgenic Tecta ENT/ ENT mice. J Neurophysiol 91: 163–171, 2004. First published October 1, 2003; 10.1152/jn.00680.2003. Distortion product otoacoustic emissions (DPOAE) were recorded from wildtype mice...

This paper proposes a m ethodology to assess the pro-poorness of governm ent fiscal policies in view of bringing m arginal reform s. A governm ent policy is said to be pro-poor if it benefits the poor proportionally m ore than the non-poor. The author first derives the poverty elasticity for the general class of poverty. Then, using the idea of poverty elasticity, she proposes a propoor index t...

OBJECTIVES/HYPOTHESIS Accurate assessment of disease activity in patients with otorhinolaryngological manifestations of granulomatosis with polyangiitis (Wegener's) (ENT/GPA) is necessary for treatment decisions and clinical trials. We have designed a disease activity score (ENT/GPA DAS) for this purpose. STUDY DESIGN A prospective cross-sectional study. METHODS GPA patients seen in a terti...