Prostaglandins exert a profound influence over the adhesive, migratory, and invasive behavior of cells during the development and progression of cancer. Cyclooxygenase-2 (COX-2) and microsomal prostaglandin E(2) synthase-1 (mPGES-1) are upregulated in inflammation and cancer. This results in the production of prostaglandin E(2) (PGE(2)), which binds to and activates G-protein-coupled prostaglan...

OBJECTIVE To investigate the relationship between the expression level of matrix-metalloproteinases (MMPs) with the pathological grades and MRI characteristics of human gliomas. METHODS Prior pre- and post-contrast enhancement MRI was performed on 31 patients with gliomas, which were confirmed by post-operational pathology. The expression of MMP-2 and MMP-9 were determined by immunohistochemi...

Environmental indicators can be used as a first stage in progress towards comprehensive environmental impact measures [J. Environ. Manage 65/3 (2002) 285]. In this article, we develop a 'pollutant interaction matrix method' that allows calculation of a global environmental protection index (Ep) in order to verify the eco-compatibility of an industrial activity. Two methods are proposed for the ...

In this work, a bio-based flame retardant (Cy-HEDP) was synthesized from cytosine and HEDP through facile salt-forming reaction embedded into epoxy matrix to improve the retardancy smoke suppression performance. The product Cy-HEDP well characterized by FTIR, 1 H 31P NMR SEM tests. On basis of results, adding 15 wt% Cy-HEDP, EP15 can pass UL-94 V-0 rating, total production (TSP) as heat release...

Sequestration and degradation of red blood cells (RBC) are believed to occur in part in the liver, but the magnitude and cellular localization of this process remain uncertain. This problem was studied in rats by investigating isolated parenehymal and sinusoidal cell populations of the liver. After digesting the perfused liver with pronase, hepatic sinusoidal cells were isolated free of RBC and...

By retrieving records from Taiwan's National Health Insurance (NHI) system's database, the current study aimed to investigate the impacts of hysterosalpingography (HSG) to patients after ectopic pregnancy (EP) operations in Taiwan.In this retrospective cohort study, insurance claims data from 1997 to 2013, derived from a cohort of 1 million people randomly sampled to represent all NHI beneficia...

ectopic pregnancy (ep) is the most important cause of maternal death in the first trimester accounting for 9 - 13% of all pregnancy-related deaths (1). despite the use of transvaginal sonography and high sensitive quantitative beta-hcg assays for diagnosis, nearly 40-50% of all eps may be initially misdiagnosed (2). therefore, several biomarkers have been investigated for early diagnosis of ep....

In situ hybridization was used to quantitate the cells that produce erythropoietin (EP) in the renal cortices of mice with varying severities of acute anemia and of mice recovering from severe, acute anemia. The number of EP-producing cells in the renal cortex increased in an exponential manner as hematocrit was decreased. Individual EP-producing cells had very similar densities of silver grain...

Hepatocellular carcinoma (HCC) is believed to originate from cancer stem cells (CSCs). While epithelial cell adhesion molecule (EpCAM) is a marker of normal hepatic stem cells (HSCs), EpCAM+ cells from HCC behave like CSCs. Since HCC mostly develops on a cirrhotic background, we sought to determine whether CSC-like EpCAM+ cells exist in patients with advanced cirrhosis. Both flow cytometry and ...

In the present work R-Matrix calculations regarding differential cross sections of natMg(p,p0)natMg elastic scattering for Ep,lab = 0.70 – 4.25 MeV were implemented using Azure2 code [1]. A coherent set sections, first to cover 2.45 energy range [2], measured at Tandem Accelerator laboratory NCSR “Demokritos” was used as a basis calculations. These results able accurately reproduce both experim...