the b cell is a vital contributor to humoral immunity. the b cell-specific antigen cd20 is expressed during b cell development, starting at the pre-b cell level and persists through b cell differentiation, but is lost during terminal differentiation to plasma cells. rituximab is a monoclonal antibody that destroys both normal and malignant b cells that have cd20 on their surfaces and is therefo...

Gingival recession can result in an unesthetic appearance, hypersensitivity, and root caries. The physiological well-being of the patient is a significant factor associated with success dental therapy.Numerous techniques are advocated for coverage. Although, connective tissue graft serves as gold standard, it requires second surgical site -a major disadvantage. When aesthetic demand high vestib...

Single cells suspensions used for grafting in the clinical setting may be reliably cryopreserved by established protocols. However, for tissue engineered constructs which now also get used as grafts in the clinic such established protocols and assays which indicate graft viability and their function as graft do not exist. a) The purpose was to develop a cryoprotocol and an animal model to test ...

Gingival recession is defined as the apical displacement of marginal gingiva in relation to cemento-enamel junction. It a common clinical finding individuals with good well those poor oral hygiene. may affect single tooth or multiple teeth simultaneously. Patients adjacent gingival recessions present major therapeutic challenge Periodontist, when it comes balancing their esthetic and functional...

nowadays, due to recent developments and researches in dental science, it is possible to preserve and restore previously extracted cases such as teeth with extensive caries, fractured or less appropriate cases for crown coverage as well as teeth with external perforation caused by restorative pins. in order to restore the teeth with preservation of periodontium, we should know thoroughly physio...

Connective tissue growth factor (CTGF) is a cysteine-rich protein that promotes extracellular matrix deposition. CTGF is selectively induced by transforming growth factor beta and des-Arg kallidin in lung fibroblasts and increases steady-state mRNA levels of alpha type I collagen, 5alpha-integrin and fibronectin in fibroblasts. Bronchial epithelial cells have been proposed to functionally inter...