This review discusses the effects and implications of active-site proximity in different bimetallic catalytic systems, strongly focusing on reduction CO 2 its reaction with epoxides hydrogen to generate value-added products.

The hydrolytic kinetic resolution (HKR) of terminal epoxides catalyzed by chiral (salen)Co(III) complex 1 x OAc affords both recovered unreacted epoxide and 1,2-diol product in highly enantioenriched form. As such, the HKR provides general access to useful, highly enantioenriched chiral building blocks that are otherwise difficult to access, from inexpensive racemic materials. The reaction has ...

Density functional theory is employed to study the reaction mechanisms of different epoxide-transforming enzymes. Calculations are based on quantum chemical active site models, which are build from X-ray crystal structures. The models are used to study conversion of various epoxides into their corresponding diols or substituted alcohols. Epoxide-transforming enzymes from three different familie...

The cationic cyclization of polyenes has proved to be a useful tool in the synthesis of natural terpenic products.1 During recent years biomimetic approaches using radical chemistry have also been described.2,3 One of the most efficient is based on Mn(III) chemistry, which in the presence of Cu(II) resolves one of the main problems involved in radical reactions, the loss of funcionality.4,5 Ano...

Poly(ester-carbonate) copolymers were synthesized through triethylborane (TEB)-activated, one-pot copolymerization of epoxides with anhydrides (AH) and CO₂. Depending upon the feeding ratio AH to epoxides, poly(ester-carbonate) random tapered ester structures could be derived due much higher reactivity toward growing oxanions compared Anhydrides like succinic anhydride (SA) phthalic (PA) when t...