The postnatal dev~loPment of short-term potentiation (STP) and .~ long-term potentiation (LIP) were examined in the neocortex and dentate , gyrus of the rat. It was. found that STP and LTP develop during narrowly , defined time periods in both systems. This functional synaptic development development formation). did not appear to~correspond well with known structural I I~ in either system (e.g....

there are some conflicts about constancy of conduction velocity (cv) in a given tract of nervous system. by recording excitatory postsynaptic currents (epsc) in layer iv of the somatosensory cortex we tried to clear changes in cv of thalamocortical tract of mice aged 3 to 50 days old. field potentials and epsc were recorded in the layer iv by stimulation of ventrobasal nucleus of thalamus (vb) ...

We investigated a presynaptic form of long-term potentiation (LTP) in horizontal slices of the rat spinal cord by visualizing presynaptic and postsynaptic excitation with a voltage-sensitive dye. To record presynaptic excitation, we stained primary afferent fibers anterogradely from the dorsal root. A single-pulse test stimulation of C fiber-activating strength to the dorsal root elicited actio...

Photonic synaptic transistors are promising neuromorphic computing systems that expected to circumvent the intrinsic limitations of von Neumann-based computation. The design and construction photonic with a facile fabrication process high-efficiency information processing ability highly desired, while it remains tremendous challenge. Herein, new approach based on spin coating blend CsPbBr3 pero...

The physiological role of taurine, one of the most abundant free amino acids in the mammalian brain, is still poorly understood. We have found that bath application of the amino acid taurine induces two opposite actions on field excitatory synaptic potentials (fEPSP) recorded in the CA1 area of hippocampal slices: a decrease in fEPSP slope prevented by GABAA antagonists, and a long-lasting pote...

Evoked excitatory postsynaptic potentials (EPSPs) were simultaneously intracellularly recorded in two lumbar motoneurons located in spinal segments 8-10 in response to intraaxonal stimulation of a descending fiber. Their mean amplitudes, paired-pulse facilitation, and short- and long-term posttetanic potentiation were compared to reveal possible functional differences among synapses formed by o...

Learning and memory require the formation of new neural networks in the brain. A key mechanism underlying this process is synaptic plasticity at excitatory synapses, which connect neurons into networks. Excitatory synaptic transmission happens when glutamate, the excitatory neurotransmitter, activates receptors on the postsynaptic neuron. Synaptic plasticity is a higher-level process in which t...

The excitability of neocortical neurons from cat association areas 5-7 was investigated during spontaneously occurring seizures with spike-wave (SW) complexes at 2-3 Hz. We tested the antidromic and orthodromic responsiveness of neocortical neurons during the "spike" and "wave" components of SW complexes, and we placed emphasis on the dynamics of excitability changes from sleeplike patterns to ...

Freir, Darragh B., Christian Holscher, and Caroline E. Herron. Blockade of long-term potentiation by b-amyloid peptides in the CA1 region of the rat hippocampus in vivo. J Neurophysiol 85: 708–713, 2001. The effect of intracerebroventricular (icv) injections of b-amyloid peptide fragments Ab[15–25], Ab[25–35], and Ab[35–25] were examined on synaptic transmission and long-term potentiation (LTP)...

We have found that bradykinin (BK) potentiates the nicotine-induced currents in airway paratracheal/parabronchial ganglia (PTG) neurons. In this study, we investigated if BK affects the cholinergic synaptic transmission in rat PTG neurons attached with synaptic buttons. Excitatory postsynaptic currents (EPSCs) were recorded in acutely dissociated PTG neurons attached with presynaptic boutons. E...