Annotation. The work aims to conduct a biophysical assessment of the charge state buccal epithelium cells (BEC), microcirculatory channel oral mucosa and fluid in patients with erosive-ulcerative form lichen planus. problem is relevant due increasing number planus patients, uncertain etiology disease, ongoing struggle find treatment solutions. 11 aged 50-60 years (erosive-ulcerative form) were ...

Oral lichen planus (OLP) is chronic inflammatory disease of the oral mucosa whose etiology is still unknown but mounting evidence points to the immunologic basis of this disorder [1]. OLP has many different forms; however, reticular type is the most frequent one. OLP is thought to be precancerous lesion with different percentages of malignant transformation reported in the literature. It is wel...

BACKGROUND Erosive lichen planus (LP) of the soles is a rare variant of LP, characterized by chronic, painful, and disabling plantar ulcerations. Herein, we report a case with complete healing following treatment with systemic steroids. CASE REPORT A 38-year-old woman was referred with painful and disabling erosive bilateral plantar LP, which she had experienced for 6 weeks. A 1 mg/kg/day, or...

BACKGROUND An association between HCV infection and lichen planus is uncertain because the prevalence of HCV infection in patients with lichen planus varies considerably from one geographic area to another. The purpose of this study was to determine the frequency of anti-HCV antibodies and its association with various clinical types of lichen planus in Mekkah, Saudi Arabia. METHODS A total of...

Lichen planus (LP), although a dermatosis, is more common in the oral mucous membrane than in the skin. Lesions of oral LP are classically found on the buccal mucosa and gingiva. Among the various types, the reticular lesions are asymptomatic and require no treatment, but pain and severe discomfort accompany the erosive or ulcerative lesions. Malignant transformation to squamous cell carcinoma ...

INTRODUCTION L ichen planus (LP) is a T-cell-mediated chronic inflammatory disease of autoimmune origin affecting the skin, nails and mucosa, including the oral cavity and rarely the esophagus. The disease is characterized histologically by a dense lichenoid (band like) lymphocytic infiltrate along the dermal epidermal junction (1). The T-cells induce the overlying keratinocytes to undergo apop...

The oral lichen planus (OLP) is a chronic inflammatory disease, probably autoimmune, with different clinical forms. The most common types are the reticular and the erosive ones. Apoptosis participates in the destruction of basal keratinocytes, but its role in the perpetuation of the subepithelial lymphocytic infiltrates was not yet investigated. To evaluate the involvement of apoptosis in the e...

Background and aims. Oral lichen planus is a common chronic inflammatory disease of the oral mucosa with malignant potential, pathogenesis of which is not still well known. Free radicals and reactive oxygen species can play an important role in the pathogenesis of oral lichen planus. The aim of this study was to investigate salivary oxidative stress and antioxidant systems in patients with oral...

oral lichen planus is diagnosed according to clinical and histopathological characteristics.some times all of the classical  histopathological features can not be seen.in some articles the presence of mast cells have been noted below the epithelium of oral lichen planus patients.the following study was done to evaluate the number of mast cells in the histopathological sections of 20 oral lichen...

background and aims. oral lichen planus is a common chronic inflammatory disease of the oral mucosa with malignant potential, pathogenesis of which is not still well known. free radicals and reactive oxygen species can play an important role in the pathogenesis of oral lichen planus. the aim of this study was to investigate salivary oxidative stress and antioxidant systems in patients with oral...