Jones HR Jr, Millikan CH: Temporal profile (clinical course) of acute carotid system cerebral infarction. Stroke 7: 64-71, 1976 Millikan CH, Siekert RG, Whisnant JP: The clinical pattern in certain types of occlusive cerebrovascular disease. Circulation 22: 1002-1010, 1960 Kubik CS, Adams RD: Occlusion of basilar artery — clinical and pathological study. Brain 69: 6-121, 1946 Millikan CH, Sieke...

Carotid Artery Stenting Before CABG: A Better Alternative to Treat Concomitant Coronary and Carotid Artery Disease To the Editor: We read with great interest the article published recently “Is There Any Benefit From Staged Carotid and Coronary Revascularization Using Carotid Stents?” by Randall et al.1 In our institution, we have a clinical research protocol regarding the management of patients...

BACKGROUND AND PURPOSE We compared the current antithrombotic strategy of antiplatelet therapy with aspirin, and anticoagulant therapy with heparin, with a specific genetically engineered chimeric antibody (c7E3 Fab) directed against the human glycoprotein IIb/IIIa receptor in an animal model of arterial thrombosis. METHODS Anesthetized cynomolgus monkeys (Macaca fascicularis) were instrument...

Parent artery ligation is an accepted treatment for intracranial aneurysms that are not amenable to a direct surgical approach. Parent artery ligation is one of the oldest effective surgical means of aneurysm therapy (the "Hunterian principle" (1 ]). Recently it has become possible to perform parent artery occlusion of the carotid or vertebral artery percutaneously by using detachable balloon t...

In this issue of Arteriosclerosis, Thrombosis and Vascular Biology, de Waard et al1 report enhanced neointima formation and luminal stenosis following carotid artery ligation in mice deficient for plasminogen activator inhibitor-1 (PAI-1) or vitronectin (VN) compared with their wildtype counterparts. Their findings appear to contradict those of a recently published study by Peng et al,2 thus ad...

A 59-year old man developed perioperative stroke following left carotid endarterectomy seconday to thrombosis at the endarterectomy site. Transcranial Doppler ultrasonography revealed very frequent microembolization in the left middle cerebral artery territory. The patient was successfully treated with intravenous abciximab with complete neurological recovery.

A case is presented in-which the detection of venous-stasis retinopathy in one eye led to investigation of the carotid circulation. There were no neurologic symptoms of carotid insufficiency, and noninvasive tests failed to reveal significant carotid pathology. Digital subtraction angiography and carotid angiography demonstrated a carotid plaque of doubtful significance. At carotid endarterecto...

artery in the neck. Obviously the pressure is not always so low and will depend on the collateral circulation which may be much better to the eye than to the brain. On the contrary, one might expect to find a near-zero low diastolic retinal artery pressure in some patients with a stroke without carotid artery occlusion but with a retinal artery stenosis or thrombosis (near-zero low pressure is ...

artery in the neck. Obviously the pressure is not always so low and will depend on the collateral circulation which may be much better to the eye than to the brain. On the contrary, one might expect to find a near-zero low diastolic retinal artery pressure in some patients with a stroke without carotid artery occlusion but with a retinal artery stenosis or thrombosis (near-zero low pressure is ...

there are epidemiologic evidences suggested an increased carotid intima/media thickness (imt) as a predictor of cardiovascular disease events. the purpose of this study was to determine the differences of imt means in patients with positive and negative coronary angiographic findings. background: we conducted a case control study on patients with typical stable angina pectoris. the case group i...