The advancement of gene-based therapeutics to the clinic is limited by the ability to deliver physiologically relevant doses of nucleic acids to target tissues safely and effectively. Over the last couple of decades, researchers have successfully employed polymer and lipid based nanoassemblies to deliver nucleic acids for the treatment of a variety of diseases. Results of phase I/II clinical ...

Understanding the nanoscale structure of polymeric micelles is challenging: their relatively small size tests limits most experimental techniques, while great conformational flexibility individual polymer chains makes deriving insight from computer simulations difficult. Pluronics and Tetronics are amphiphilic block copolymers based on poly(ethylene oxide) poly(propylene blocks that self-assemb...

We describe the synthesis of [bis(N-(3-tert-butylsalicylidene)anilinato)] titanium (IV) dichloride (Ti-FI complex) and examine the effects of comonomer (feed concentration and type) on its catalytic performance and properties of the resulting polymers. Ethylene/1-hexene and ethylene/1-octene copolymers were prepared through copolymerization using Ti-FI catalyst, activated by MAO cocatalyst at 3...

In this work, we have conducted in situ simultaneous small- and wide-angle X-ray scattering Raman spectroscopy experiments to investigate the fundamental differences mechanism of mesomorphic α phase transition isotactic polypropylene homopolymer random ethylene–propylene copolymer. Via quantitative analysis results coming from three techniques, found that homopolymer, chain interlock extension ...

The adsorption thermodynamics of copolymers, based on ethylene oxide (EO) and propylene oxide (PO) units, at the laponite (RD) clay/liquid interface was determined at 298 K. The copolymer nature was tuned at molecular level by changing the hydrophilicity, the architecture and the molecular weight (Mw) keeping constant the EO/PO ratio. Polyethylene (PEGs) and polypropylene (PPGs) glycols with va...

l'auteur explique le comportement des esters cycliques neutres vis -a- vis de l'eau ,de l'acide chlorhydrique , ainsi que la polymerisation des ethylphosphates cycliques d'ethylene et de propylene par des traces d'eau. les produits resultant de la plymerisation de ce dernicr phosphate cyclique sont plus complexes que ceux obtenus dans les memes conditions avec 1'et...

Fisher-Tropsch synthesis (FTS) is a promising method to make alternative hydrocarbons from biomass or other resources. Upgrading the primary FTS products of considerable interest. Cracking FT wax economically attractive produce light olefins. Herein, effects zeolite type, Si/Al ratio ZSM-5, and reaction condition on catalytic cracking were investigated. It was found that pore structure acid pro...

Exceptional high quality ZIF-8 membranes prepared through a novel seeded growth method in aqueous solutions at near room temperature exhibit excellent separation performance for C2/C3 hydrocarbon mixtures. The separation factors for mixtures of ethane/propane, ethylene/propylene and ethylene/propane are ∼80, ∼10 and ∼167, respectively.