Establishing the credibility of existing data is an ongoing issue, particularly when the data sets are to be used for a secondary purpose, i.e., not the original reason for which they were collected. If the secondary purpose is similar to the primary purpose, the potential user may have little difficulty establishing credibility since the acceptance criteria for both purposes should be similar....

OBJECTIVE To establish a more accurate indication for endoscopic third ventriculostomy (ETV) in patients with noncommunicating hydrocephalus through the analysis of the evolution of postoperative mean intracranial pressure (ICPM). METHOD Intracranial pressure (ICP) was recorded overnight during 8-hour periods with an intraventricular probe. A personal computer connected to the ICP monitor min...

BACKGROUND We aimed to develop a quantitative assay to measure duck HBV (DHBV) DNA in single hepatocyte nuclei from DHBV-infected animals and to observe intranuclear DHBV DNA kinetics undergoing entecavir (ETV) therapy. METHODS DHBV DNA in isolated nuclei was amplified by quantitative real-time PCR. Liver tissues from chronically-infected ducks with or without ETV treatment were assessed. Cel...

A porcine torovirus (PoTV) was identified and characterized; it is a novel member of the genus Torovirus (family Coronaviridae, order Nidovirales), closely related to but clearly distinct from the already recognized equine torovirus (ETV) and bovine torovirus (BoTV) representatives. Immunoelectron microscopy of feces from piglets revealed elongated, 120- by 55-nm particles which were recognized...

INTRODUCTION idiopathic normal pressure hydrocephalus (INPH) is characterized by gait apraxia, cognitive dysfunction and urinary incontinence. There are two main treatment options: ventriculoperitoneal shunt (VPS) and endoscopic third ventriculostomy (ETV). However, there are doubts about which modality is superior and what type of valve should be applied. We are summarizing the current evidenc...

OBJECTIVE To investigate the efficacy of endoscopic third ventriculostomy (ETV) for infantile hydrocephalus. METHODS Retrospectively reviewed the 17 infantile hydrocephalus cases who were treated with ETV between July 2009 and June 2013. The study includes 17 patients (4 Han and 13 Hui) between the ages of 51 and 337 days. Five cases with encephalitis history and 2 cases with cerebral hemorrh...

To evaluate whether PAF is related to the precipitation of pulmonary edema after myocardial ischemia, we studied the effect of a specific PAF antagonist, CV-6209, on the extravascular lung water level measured by the thermal-dye double indicator dilution method, ETV, after coronary ligation in dogs. Eight dogs served as sham control animals (group 1). The proximal left anterior descending coron...

Background: In chronic hepatitis B patients with or exposed to the risk of osteoporosis renal dysfunction, switching from tenofovir disoproxil fumarate (TDF) alafenamide (TAF) entecavir (ETV) may be right choice. Objectives: This study aimed present real-life data in terms efficacy and safety a TAF/ETV treatment change while receiving TDF. Methods: retrospective was conducted on 344 adult 10 ce...

Traditional machine learning sequence models, such as RNN and LSTM, can solve sequential data problems with the use of internal memory states. However, neuron units weights are shared at each time step to reduce computational costs, limiting their ability learn time-varying relationships between model inputs outputs. In this context, paper proposes two methods characterize dynamic in real-world...

BACKGROUND & AIMS Virological breakthrough (VBT) could be a manifestation of chronic hepatitis B (CHB) in patients treated with long-term nucleot(s)ide analogues. We aimed to determine the association of on-treatment serum hepatitis B virus (HBV) DNA with VBT in HBeAg-positive CHB patients receiving entecavir (ETV) treatment. METHODS A retrospective cohort study, including 162 consecutive pat...