conclusions it was shown that combination of pectin and eudragits can relatively control drug release in the upper gi. on the other hand, pectin degraded in the presence of pectinase and formulations were susceptible to the colonic media. results it was shown that in the presence of pectin, formulations without erl had a relative resistance to drug release in sgf. pellets containing pectin and ...

OBJECTIVES Ketotifen fumarate (KF) is a selective and noncompetitive histamine antagonist (H1-receptor) that is used topically in the treatment of allergic conditions of rhinitis and conjunctivitis. The aim of this study was to formulate and improve an ophthalmic delivery system of KF. Ocular nanoparticles were prepared with the objective of reducing the frequency of administration and obtainin...

Polymers constitute the major part of pharmaceutical formulations functionality and significance. Development of novel drug delivery system (NDDS) has been made possible by eudragit polymers to modify the release pattern of drug. The basic objective of sustained drug release is to achieve more effective therapies by eliminating potential for both under and overdosing. Other advantages include m...

In the present study, a capsule formulation composed of enteric coated granules of Lactobacillus acidophilus ATCC 4962 was developed using Eudragit L30D-55 as enteric polymer. Optimization of the capsule formulation was achieved with a maximum viable cell count after 2 h of incubation in acid medium and disintegration time of 1 h in buffer pH 6.8. The amount of Eudragit L30D-55 in the capsules ...

In an era moving towards digital health, 3D printing has successfully proven its applicability in providing personalised medicine through a technology-based approach. Among the different techniques, direct extrusion been demonstrated as promising approach for on demand manufacturing of solid dosage forms. However, it usually requires use elevated temperatures and/or incorporation evaporable sol...

HN Shivakumar, et al., (2007), Fabricated & evaluation of pH sensitive Minitablets for chronotherapeutic delivery of theophylline using different coat weights of eudragit S-100 to be applied to the drug loaded core mini-tablets. The study showed that the coat weight of 10% weight gain was sufficient to impart an excellent gastro resistant property to the tablets for effective release of the dru...