Accurate spatiotemporal assessment of extracellular vesicle (EV) delivery and cargo RNA translation requires specific and robust live-cell imaging technologies. Here we engineer optical reporters to label multiple EV populations for visualization and tracking of tumour EV release, uptake and exchange between cell populations both in culture and in vivo. Enhanced green fluorescence protein (EGFP...

BACKGROUND Human non-polio enterovirus (EV) and human parechovirus (HPeV) are important pathogens of viral infection and aseptic meningitis in children. The aim of this study is to prospectively compare the incidence, clinical signs, blood and cerebrospinal fluid in EV and HPeV infected children. OBJECTIVES To compare the clinical symptoms and laboratory data of children with different EV and...

The purpose of this paper is twofold. First we derive theoretically, using appropriate transformation on x(n), the closed-form solution of the nonlinear difference equation x(n+1) = 1/(±1 + x(n)), n ∈ N_0. The form of solution of this equation, however, was first obtained in [10] but through induction principle. Then, with the solution of the above equation at hand, we prove a case ...

BACKGROUND The aim of this study was to investigate the usefulness of contrast-enhanced ultrasonography (CEUS) in predicting of esophageal varices (EV) and assessing high-risk EV in patients with hepatitis B virus (HBV)-related cirrhosis. MATERIAL AND METHODS Patients with HBV-related cirrhosis who had undergone endoscopy were prospectively recruited. Hepatic dynamic CEUS was performed. Regions...

Poliomyelitis associated with circulating vaccine-derived polioviruses (cVDPVs) is a serious public health issue in the post-eradication era, and the occurrence of recombinant cVDPVs emphasizes the need to elucidate enterovirus C (EV-C) epidemiology. Stool samples were collected from 826 healthy children in Southern Xinjiang in 2011 to investigate EV-C circulation and epidemiology. Thirty-six E...

Enterovirus B81 (EV-B81) is a newly identified serotype within the species enterovirus B (EV-B). To date, only eight nucleotide sequences of EV-B81 have been published and only one full-length genome sequence (the prototype strain) has been made available in the GenBank database. Here, we report the full-length genome sequences of two EV-B81 strains isolated in the Tibet Autonomous Region of Ch...

Extracellular vesicles (EVs) are thought to exert protective effects after ischemic and remote ischemic preconditioning. It is not well understood which EV content factors are most relevant for protective effects. We hypothesize that ischemic preconditioning leads to qualitative changes in EV mRNA content and quantitative changes in EV size and number.Using an in vivo porcine ischemic precondit...

In this paper, we show that for any finite order entire function $f(z)$, the function of the form $f(z)^{n}[f(z+c)-f(z)]^{s}$ has no nonzero finite Picard exceptional value for all nonnegative integers $n, s$ satisfying $ngeq 3$, which can be viewed as a different result on Hayman conjecture. We also obtain some uniqueness theorems for difference polynomials of entire functions sharing one comm...