Systemic capillary leak syndrome (SCLS) is a rare and potentially fatal disorder which causes recurrent episodes of hypovolemic shock due to a markedly increased plasma shift into the interstitial space. Patients with SCLS have a characteristic triad of hypotensive shock, hypoalbuminemia and hemoconcentration. Treatment of the acute phase is supportive, focusing on adequate but not overzealous ...

ABOUT THIS POLICY: Arbor Health Plan has developed clinical policies to assist with making coverage determinations. Arbor Health Plan’s clinical policies are based on guidelines from established industry sources, such as the Centers for Medicare & Medicaid Services (CMS), state regulatory agencies, the American Medical Association (AMA), medical specialty professional societies, and peer-review...

BACKGROUND This study evaluated the processes of curricular change and the initial outcomes of the Undergraduate Medical Education for the 21st Century (UME-21) project at 18 schools. METHODS Site visits were conducted at eight partner schools in 1999 and 2001. Written proposals, progress reports, and final reports of 18 schools were reviewed. Senior medical students' responses to questionnai...

Introduction: To address the need for greater standardization within the field of electrodiagnostic medicine, the Normative Data Task Force (NDTF) was formed to identify nerve conduction studies (NCS) in the literature, evaluate them using consensus-based methodological criteria derived by the NDTF, and identify those suitable as a resource for NCS metrics. Methods: A comprehensive literature s...

C ystic fibrosis–related diabetes (CFRD) is the most common comorbidity in subjects with cystic fibrosis (CF). A consensus conference on CFRD was cosponsored by the Cystic Fibrosis Foundation (CFF), the American Diabetes Association (ADA), and the Pediatric Endocrine Society (PES) in September 2009. The committee’s evidencebased recommendations for clinical management of CFRD are published in t...

A study of patients with stable angina and moderate left ventricular systolic dysfunction has shown that the addition of ivabradine to bisoprolol produced additional anti-anginal and anti-ischaemic effects that were not achieved with up-titration of bisoprolol. This indicative study is of importance to clinicians as they are frequently faced with patients on beta-blockers who are not able to to...

A survey has been given of the development of voice in adolescents. The voice parameters fundamental frequency during reading of a standard text and phonetograms where compared with the pubertal development and the androgens and estrogens in boys and girls respectively. The review of adolescent voice development in girls and boys briefly present the core results of the study “Normal Development...

The goal of this program is to use implementation science methods to evaluate strategies that increase the effectiveness of Early Childhood Development (ECD) programming and improve developmental outcomes for infants and young children affected by HIV/AIDS. This goal will be achieved by working with local partners and community based organizations to implement evidencebased family oriented and ...

Local infiltration analgesia (LIA) has been introduced recently as a promising step forward in reducing postoperative pain and side effects from analgesics after knee arthroplasty and, so far, with less convincing results after hip artroplasty. As often with new methods, there is a way to go from the first, enthusiastic, nonblinded case series to evidencebased recommendations for clinical, ever...

I diopathic pulmonary fibrosis (IPF) is increasingly recognised as a well-known clinical and highly complex entity associated with poor prognosis and a median survival of 3–5 yrs after the diagnosis is made. The importance of the need for an accurate diagnosis and appropriate clinical management is evident. In this regard, the first statement/guidelines on the clinical management of IPF, jointl...