Chronic pancreatitis (CP) is a progressive inflammatory process that causes irreversible damage to the pancreas due fibrosis and scarring. The incidence of CP varies among regions. Alcohol consumption smoking are main aetiologicalfactors CP. In addition, autoimmune diseases, hereditary genetic factors, tropical also contribute this condition. Though no single mechanism has been shown initiate p...

An ectopic pancreas is defined as pancreatic tissue outside its normal location, anatomically separated from the pancreas.The transcription factor pancreas/duodenum homeobox protein 1 (PDX1) involved in maintaining and functions early development, beta cell differentiation, endocrine non cells. Pancreatic subunit alpha (PTF1A) affects exocrine formation regulation of acinar identity, expressed ...

Abstract Tissue kallikrein (kallikrein 1) was first identified in pancreas and is the namesake of the kallikrein-related peptidase (KLK) family. KLK1 and the other 14 members of the human KLK family are encoded by 15 serine protease genes clustered at chromosome 19q13.4. Our Northern blot analysis of 19 normal human tissues for expression of KLK4 to KLK15 identified pancreas as a common express...