A 3%-year-old boy presented with a midline 1.5 X 1.5 X 1 cm. cystic swelling on the ventral apsect of the middle third of the penis 2 years in duration. There was no history of urinary tract infection, hematuria, dysuria, trauma, difficult voiding or variation in the size of the swelling in relation to micturition. The urinary stream was normal. The skin overlying the swelling was normal and fr...

PURPOSE Lower urinary tract malformations are among the most common congenital anomalies in humans. Molecular genetic studies of mouse external genital development have begun to identify mechanisms that pattern the genital tubercle and orchestrate urethral tubulogenesis. The urethral plate epithelium is an endodermal signaling region that has an essential role in external genital development. H...

External genital development begins with formation of paired genital swellings, which develop into the genital tubercle. Proximodistal outgrowth and axial patterning of the genital tubercle are coordinated to give rise to the penis or clitoris. The genital tubercle consists of lateral plate mesoderm, surface ectoderm, and endodermal urethral epithelium derived from the urogenital sinus. We have...

OBJECTIVE To evaluate the effect of a single cystoscopic injection of botulinum toxin to the external urethral sphincter in treating detrusor external sphincter dyssynergia. DESIGN An open treatment trial with pre- and post-treatment evaluations. SUBJECTS A total of 20 suprasacral spinal cord injured patients with pure detrusor external sphincter dyssynergia. METHODS A single dose of 100 ...

UNLABELLED Maintenance of ear projection and post auricular sulcus in staged ear reconstruction in microtia is a trying problem. So also is the maintenance of the patency of the external auditory meatus following recanalization and meatoplasty. Numerous splints and dressing techniques have been described for the above situations. Some of the problems encountered include the availability of the ...