Paragangliomas are very rarely seen in the nose, paranasal sinuses and nasopharynx. The development of paraganglioma concurrently with nasopharyngeal carcinoma in the same region has not been reported to date. In this study we reported a 59-years-old a female case of nasopharyngeal carcinoma who underwent radiotherapy six years ago and got the diagnosis of sinonasal paraganglioma in the same re...

Paragangliomas of the orbit are extremely rare. A case of an orbital paraganglioma, including the first magnetic resonance imaging description of this tumour is described here. The patient underwent surgery with gross total removal of the tumour and relief of his initial chief complaint of visual blurring. The differential diagnosis and therapeutic options for the management of this tumour are ...

Gangliocytic paraganglioma (GP) has been regarded as a rare benign tumor that commonly arises from the second part of the duodenum. As GP does not exhibit either prominent mitotic activity or Ki-67 immunoreactivity, it is often misdiagnosed as neuroendocrine tumor (NET) G1. However, the prognosis might be better in patients with GP than in those with NET G1. Therefore, it is important to differ...

Twenty-six cases of surgically verified nonchromaffin paragangliomas (NCPs) of the temporal bone were investigated by contrast-enhanced, thin-section, multiplanar high-resolution computed tomography (CT). Based on the high-resolution CT findings the tumors were classified according to a recently introduced surgical classification of NCP into four main types (A, B, C1-C3, and D1-D3). With high-r...

We report on an original case of a 64 year old lady diagnosed with an extraadrenal mesenteric paraganglioma associated with an incidental histological finding of a gallbladder paraganglion. Paragangliomas are rare neuroendocrine, neural crest-derived tumours, found in diverse locations and display variable catecholamine secreting behaviour. Malignant potential can be difficult to predict on his...

BACKGROUND Adenomas of the adrenal gland are rare causes of virilization in childhood. CASE REPORT A girl aged 2 years and 4 months presented with pubarche, distinct clitoral hypertrophy, tall stature, and increased height velocity. Plasma testosterone and dehydroepiandrosterone were elevated. Androgens remained unchanged after adrenocorticotropic hormone, and dexamethasone administrations. U...

Tumours arising in the chemoreceptor system are termed chemodectomas. Intrathoracic chemodectoma is a rare tumour, only 74 cases having been described by 1977.1 Systemic catecholamine secretion by an intrathoracic chemodectoma is very uncommon andwe have been able to trace only one other published case report of proven catecholamine secretion. We describe a second case and discuss briefly these...

Aim We seek a simple and reliable tool to predict malignant behavior of pheochromocytoma paraganglioma (PPGL). Methods This single-center prospective cohort study assessed size primary PPGLs on preoperative cross-sectional imaging prospectively scored specimens using the Pheochromocytoma Adrenal Gland Scaled Score (PASS). Multiplication PASS points with maximum lesion diameter (in mm) yielded S...

A 30-year-old woman with severe hypertension was admitted to the hospital with a history of headache, palpitations, and diaphoresis following sexual intercourse. Twenty-four hour urinary excretion of free catecholamines and metabolites was markedly increased as was serum chromogranin A. Computed tomography scan revealed a large mass in the left adnex site and magnetic resonance imaging confirme...

Paragangliomas are benign neoplasms that arise from the autonomic nervous system and the associated paraganglia. Although benign, they have been shown to possess metastatic potential. Extra-adrenal retroperitoneal paraganglioma with vertebral metastasis is considered very uncommon. Here, we present a case of a functional extra-adrenal paraganglioma of the retroperitoneum giving metastasis to T4...