We present a case of eclampsia complicated by alexia without agraphia. To our knowledge, this syndrome has never before been described in the literature.

The network structure of the plant circadian clock is complex and direct regulatory interactions between individual components have proven particularly difficult to predict from genetic analyses. Here, we systematically investigate in vivo binding interactions between the morning-specific transcription factor, LATE ELONGATED HYPOCOTYL (LHY) and the promoters of other components of the network. ...

Circadian clocks are autoregulatory, endogenous mechanisms that allow organisms, from bacteria to humans, to advantageously time a wide range of activities within 24-hr environmental cycles. CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) and LATE ELONGATED HYPOCOTYL (LHY) are thought to be important components of the circadian clock in the model plant Arabidopsis. The similar circadian phenotypes of lines...

It has long been known that the " prothrombin " time of a specimen of plasma to which has been added a brain extract thromboplastin depends on the presence of other factors in addition to prothrombin. Biggs, Douglas, and Macfarlane (1953) have demonstrated that both factor V and factor VII take part in a preliminary reaction with the brain extract to produce an activated thromboplastin. Hardist...

BACKGROUND AND OBJECTIVES A complex haplotype of factor V gene (FV HR2) has been recently reported. FVHR2 possesses decreased co-factor activity to APC in the degradation of FVIIIa, and an increased ratio of the more procoagulant isoform FV1 compared to FV2. Contrasting results on whether the haplotype induces a significant risk of venous thromboembolism (VTE) have been reported. DESIGN AND M...

The aim of this review was to compile published data on factor V 1691 G-A alteration in a healthy Turkish population and also to stimulate the reporting of unpublished data, in order to create a map for factor V Leiden (FVL) in Turkey. From a total of 4276 healthy individuals from 26 different centers of Turkey, 345 FVL carriers (7.9%) were determined. FVL was strikingly high among newborns fro...

target. Whereas our method involves the additional cost associated with the need for dual-labeling of the probes, it has the advantage of being compatible with performance under standard PCR conditions, regardless of the SNP to be assayed. This characteristic makes it feasible to assay simultaneously, on the same 96or 384-well plate, a variety of SNPs. Interestingly, we noted that our factor V ...

One hundred years of research (1916–2016) on intellectually precocious youth is reviewed, painting a portrait of an extraordinary source of human capital and the kinds of learning opportunities needed to facilitate exceptional accomplishments, life satisfaction, and positive growth. The focus is on those studies conducted on individuals within the top 1% in general or specific (mathematical, sp...

The binding of class II Escherichia coli heat-labile enterotoxins (LT) to Y1 tissue-cultured cells and mouse intestinal cells was studied and compared with that of class I toxins, including cholera enterotoxin. All radioiodinated (125I) toxins retained their biological activities in both model systems, but only LTIIb could be shown to bind specifically to target cells. LTIIa could inhibit the b...