Background—Fascioliasis is a parasitic infection, primarily of the liver but after several weeks the biliary tract may also be aVected, related to the trematode Fasciola hepatica. The trematode is distributed worldwide in herbivores but is unusual in humans. Several outbreaks have been attributed to consumption of contaminated watercress and water. The optimal treatment of fascioliasis, particu...

With the objective of studying the role of wild fauna in the epidemiology of fasciolosis disease, a definitive wild-host inventory was carried out in a french farm where infected domestic hosts (cows) cohabit with wild potential ones. Liver flukes, faecal eggs and antibodies were looked for in lagomorphs (Oryctolagus cuniculus) and rodents (Myocastor coypus, Ondatra zybethicus, Rattus norvegicu...

introduction iran is amongst endemic countries for fasciola hepatica. individuals can become infected by consumption of contaminated uncooked green vegetables. in the chronic cases, symptoms are fever, vague abdominal pain with eosinophilia. patients sometimes have symptoms and signs of hepatobiliary involvements such as cholangitis and cholecystitis. case presentation here we present a unique ...

Experimental infections of Galba sp. (origin, Colombia) with allopatric isolates of Fasciola hepatica from France or Fascioloides magna from the Czech Republic were carried out during five successive snail generations to determine if this lymnaeid might sustain complete larval development of either parasite. In snails exposed to F. hepatica, 7 of 400 snails harboured several rediae and only two...

background: we evaluated the genetic diversity of samples identified morphologically as fasciola spp. from sheep, cattle and goat from kermanshah province, western iran using pcr-rflp method. methods: we used pcr-rflp analysis of ribosomal its1 fragment using rsai restriction enzyme to investigate the genetic characteristics of fasciola species obtained from different hosts (16 sheep, 28 cattle,...

background: fasciola hepatica is one of the most important helminthes parasites and triclabendazole (tcbz) is routinely used for treatment of infected people and animals. secreted protease enzymes by the f. hepatica plays a critical role in the inva-sion, migration, nutrition and the survival of parasite and are key targets for novel drugs and vaccines. the aim of study was to determine the pro...

introduction: to determine an indicator for triclabendazole (tcbz) efficacy, alanine aminotransferase (alt) activity in fasciola hepatica (iranian isolate) parasite in presence and absence of tcbz was evaluated by an in vitro cultivation method. also, alt enzyme activity between none and parasitized-infected sheep liver tissues was assessed. method:  the sheep livers were collected and transfer...

Eggs of Fasciola hepatica were exposed for 10 days to extremely low frequency magnetic field (ELFMF) at the frequency of 50 Hz and density of 2 mT (rms). The results show an accelerated hatching of F. hepatica eggs in relation to control (non-exposed) group. The host snails, Lymnaea truncatula, were divided into three groups; those of groups I and II were infected with the miracidia of F. hepat...

background: fascioliasis caused by fasciola hepatica and f. gigantica is a foodborne and waterborne zoonotic disease with a worldwide distribution. the illness occurs in regions with intensive sheep or cattle production. in some parts of iran the incidence of human infection has increased over the past decades. since chaharmahal and bakhtiyari province has been known as a main pole of tradition...

background: the purpose of this comparative study was to detect superoxide dismutase (sod) activities in fasciola hepatica, f. gigantica parasites, infected and healthy liver tissues in order to determine of species effects and liver infection on sods activity level. methods: fasciola spp. parasites and sheep liver tissues (healthy and infected liver tissues), 10 samples for each, were collecte...