Background: Serum prolactin level has been used as an alternative determinant to help differentiate epileptic from non-epileptic seizures. We aimed to analyze the association between serum prolactin concentration and epileptic seizure versus febrile seizure as well as seizure duration, single versus multiple seizure attacks and time lapse between seizure onset and blood sampling. Methods: Seven...

Febrile seizures are usually considered relatively benign. Although some cases of sudden unexplained death in childhood have a history of febrile seizures, no documented case of febrile seizure-induced death has been reported. Here, we describe a child with complex febrile seizures who died suddenly and unexpectedly after a suspected seizure while in bed at night during the beginning phases of ...

CONTEXT Influenza virus is a major cause of illness, disruption to daily life, and increased use of health care in all age groups. OBJECTIVE To assess the safety and effectiveness of intranasally administered trivalent, live, attenuated influenza virus (LAIV) vaccine for reducing illness, absenteeism, and health care use among healthy, working adults. DESIGN Randomized, double-blind, placeb...

The aims of this study were to i) reveal the population pharmacokinetics; and ii) assess the probability of target attainment (PTA) and cumulative fraction of response (CFR) (defined as the expected population PTA for a specific drug dose and a specific population of microorganisms) of imipenem in febrile neutropenic patients with bacteraemia. Ten patients were randomised into two groups: Group...

Three hundred and three children with febrile convulsions were identified in a national birth cohort of 13 135 children followed up from birth to the age of 5 years. Breech delivery (p less than 0.05) was the only significantly associated prenatal or perinatal factor. There were no associations with socioeconomic factors. Excluding the 13 known to be neurologically abnormal before their first f...

Cerebrospinal fluid samples collected from 23 children with neurologic symptoms, such as febrile seizures, status epilepticus, and transient altered states of consciousness, associated with acute febrile illness, were examined for infectious virus by cell culture. Enteroviruses (echovirus type 9 and coxsackievirus B3) were isolated from 2 of the cerebrospinal fluid samples. The samples were als...