Abstract The main objective of this study was to prepare colon-specific pellets of budesonide using pectin as film coating.  Pellet cores of budesonide were prepared by extrusion / spheronization technique. Pectin, in different ratios was combined with Eudragit RS30D, Eudragit NE30D or Surelease to produce film coating. The dissolution profiles of pectin coated pellets were investigated in pH o...

BACKGROUND Our goal is to optimize stem cell-based tissue engineering strategies in the context of the intervertebral disc environment. We explored the benefits of co-culturing nucleus pulposus cells (NPC) and adult mesenchymal stem cells (MSC) using a novel spherical bilaminar pellet culture system where one cell type is enclosed in a sphere of the other cell type. Our 3D system provides a str...

agglomeration followed by pelleting is an efficient method to decrease transport costs and increase economic efficiency of composting municipal waste. the moisture content of compost is the most important parameter of the pellet making process for any type of manufacturing device. the experiments in this study were done at moisture contents of 35%, 45% and 50% at extruder shaft rotational speed...

in this paper the numerical simulation and operation comparison of two sizes of air gun pellets with 4.5 and 5.5 mm calibers is performed. these pellets affected by drag force and are encountered to continuous velocity variations and experience an unsteady flow. in order to solve this problem numerically, the navier- stokes equations in an unsteady compressible turbulent flow with the dynamical...

PURPOSE The study looked into the feasibility of producing pellet using Avicel CL611 as spheronization aid by the extrusion/spheronization technique. METHODS Pellets were formulated to contain either 20% or 40% Avicel CL611 and lactose monohydrate as the other sole ingredient. Water is used as liquid binder. Quality of pellets and extrudates were analyzed for size distribution, shape, surface...

The penaeid shrimp farming industry is a fast-growing sector which continues to suffer from significant feeding inefficiencies. Shrimp are slow feed on pellets, with consumption dependent wide range of environmental and physiological parameters. Feed management farms remains mainly based trays can be difficult observe often result in overfeeding. While our understanding behaviour beginning impr...

Bile salt/phospholipid mixed micelles (MMs) are potent carriers used for oral absorption of drugs that are poorly soluble in water; however, there are many limitations associated with liquid formulations. In the current study, the feasibility of preparing bile salt/phospholipid MM precursor (preMM) pellets with high oral bioavailability, using fluid-bed coating technology, was examined. In this...

Three size classes of Capitella capitata (Type I ) were fed 4 size ranges of detritus particles derived from red seaweed Gracilaria foliifera. Growth was generally reduced when only the largest particle-size range (150 to 250 pm) was available, and the effect was most pronounced for small worms. Worms lost weight when fed fecal pellets comparable in size to the largest particles of seaweed detr...