The current through nanostructures like quantum dots can be stabilized by a classical feedback loop that continuously adjusts system parameters as a function of the number of tunnelled particles n. At large times, the feedback loop freezes the fluctuations of n, which leads to highly accurate, continuous single particle transfers. For the simplest case of feedback acting simultaneously on all s...

The Cartesian feedback technique is an extended solution for reducing the distortions generated by the nonlinearities of power RF amplifiers, being its restrictions of use related to the stability margins of the lineariser loop. Here, considerations are given to its use in the Ka-band, where the small wavelengths lead to critical times and phase unbalances which produce misadjustments of the fe...

We formulated a computational model for a MAPK signaling cascade downstream of the EGF receptor to investigate how interlinked positive and negative feedback loops process EGF signals into ERK pulses of constant amplitude but dose-dependent duration and frequency. A positive feedback loop involving RAS and SOS, which leads to bistability and allows for switch-like responses to inputs, is nested...

A simple three-component negative feedback loop is a recurring motif in biochemical oscillators. This motif oscillates as it has the three necessary ingredients for oscillations: a three-step delay, negative feedback, and nonlinearity in the loop. However, to oscillate, this motif under the common Goodwin formulation requires a high degree of cooperativity (a measure of nonlinearity) in the fee...

By using a quadratic compensation slope, a CMOS current-mode buck DC-DC converter with constant frequency characteristics over wide input and output voltage ranges has been developed. The use of a quadratic slope instead of a conventional linear slope makes both the damping factor in the transfer function and the frequency bandwidth of the current feedback loop independent of the converter’s ou...

Approaches to self-adaptive software systems use models at runtime to leverage benefits of model-driven engineering (MDE) for providing views on running systems and for engineering feedback loops. Most of these approaches focus on causally connecting runtime models and running systems, and just apply typical MDE techniques, like model transformation, or well-known techniques, like event-conditi...

Oscillatory network dynamics are implicated in the functioning of healthy neural circuits and in disease pathology. Manipulating or controlling oscillatory dynamics hence has potential applications both for probing the functional role of oscillations in neural computation and as a therapeutic tool. We have explored the potential of closed-loop optogenetic feedback to manipulate oscillatory netw...

In previous papers ([2], [3], [6]) feedback guided loop scheduling algorithms have been shown to be very effective for certain loop scheduling problems. In particular they perform well for problems that involve a sequential outer loop and a parallel inner loop, and timing information gathered during one execution of the parallel inner loop can be used to inform the scheduling of the subsequent ...

In previous papers ([2], [3], [7]) feedback guided loop scheduling algorithms have been shown to be very effective for certain loop scheduling problems. In particular they perform well for problems that involve a sequential outer loop and a parallel inner loop, and timing information gathered during one execution of the parallel inner loop can be used to inform the scheduling of the subsequent ...