This paper is dealing with a new research and development platform for the development of Factory of the Future Production System, referred to as ZIMS (Zilina Intelligent Manufacturing System). ZIMS is a new, open and collaborative environment, supporting creativity, inventing new solutions and their practical implementation in the form of new innovative products. ZIMS is based on holonic based...

This paper briefly discusses a paradigm shift in manufacturing around the beginning of the 1900s. Implications for Hong Kong manufacturing industry companies and IE education are discussed.

Gastroschisis is an increasingly common malformation with unique fetal complications. Although it is usually an isolated defect, gastroschisis has a significant mortality rate of 5–10%. Complications include bowel damage, but growth retardation, oligohydramnios and fetal distress in labour are also common. There have been recent data that may help explain some of these observations, which will ...

Intrauterine growth retardation (IUGR) refers to fetal growth that has been constrained in utero. It results in newborns that have not attained their full growth potential and are already malnourished at birth. Fetuses that suffer from growth retardation have higher perinatal morbidity and mortality and are more likely to experience poor cognitive development and neurologic impairment during ch...

In the fetal alcohol syndrome (FAS) there is severe physical growth retardation both prenatally and postnatally. Secretion of growth hormone (GH) after insulin-induced hypoglycaemia and arginine infusion was analysed in 5 cases of FAS to find out whether changes in GH secretion might account for the abnormal growth pattern. Results showed a normal or slight hyper-response of GH up to 150 ng/ml,...

The problem of objectivity in histopathology is illustrated by an attempt to determine the normal range and significance of two observations, placental weight and secondary ossification, made in perinatal pathology. Neither offered a satisfactory estimation of fetal maturity. The placental weight provided little evidence of any primary placental dysfunction: the placenta was very small in assoc...

Background: Intrauterine growth retardation (IUGR), that is, an estimated fetal weight less than ten percent of the standard weight for gestational age, is one of the important challenges in modern obstetrics, the management and treatment of which is cause-dependent. Given the lack of an accepted treatment for these patients, this study aimed to introduce a treatment commonly u...

Accurate navigation by a neuronal growth cone requires the modulation of the growth cone's responsiveness to spatial and temporal changes in expression of guidance cues. These adaptations involve local protein synthesis and turnover in growth cones and distal axons.

Wiring up the nervous system depends on the precise guidance of axonal growth cones to their targets. A key mechanism underlying this guidance is chemotaxis, whereby growth cones detect and follow molecular gradients. Although recent work has uncovered many of the molecules involved in this process, the mechanisms underlying chemotactic axon guidance are still unclear. Here we compare growth co...