Inorganic polyphosphate (polyP) is composed of linear chains of phosphate groups linked by high-energy phosphoanhydride bonds. However, this simple, ubiquitous molecule remains poorly understood. The use of nonstandardized analytical methods has contributed to this lack of clarity. By using improved polyacrylamide gel electrophoresis we were able to visualize polyP extracted from Dictyostelium ...

INTRODUCTION Inflammatory fibroid polyp of the large intestine is uncommon. To our knowledge, this condition has not been reported in a patient with neurofibromatosis. CLINICAL PICTURE In this report, a 66-year-old woman with neurofibromatosis was found to have a large polyp in the caecum. TREATMENT Right hemicolectomy was performed because of the size of the polyp. OUTCOME Pathological e...

Background: Congenital lobar emphysema, also called infantile lobar emphysema, is a respiratory disease that occurs in infants when air enters the lungs and cannot leave easily. It results from cartilage deficiency and bronchomalacia causing distal air trapping and respiratory distress. In this study, we present a case of endobronchial polyp mimicking congenital lobar emphysema. Case presentati...

Polyphosphate (polyP), a polymer of orthophosphate moieties released from the dense granules of activated platelets, is a procoagulant agent. Inositol pyrophosphates, another group of phosphate-rich molecules, consist of mono- and diphosphates substituted on an inositol ring. Diphosphoinositol pentakisphosphate (IP7), the most abundant inositol pyrophosphate, is synthesized on phosphorylation o...

Polypectomy is the standard therapy for gastrointestinal pedunculated polyps [1]. However, achieving effective countertraction to snare the stalk of the polyp located in the direction of gravity can sometimes be difficult [2]. Herein, we present a case of a large gastric polyp located on the greater curvature of the gastric body that was resected using the “water immersion” technique in order t...

Computational intelligent systems could reduce polyp miss rate in colonoscopy for colon cancer diagnosis and, thus, increase the efficiency of the procedure. One of the main problems of existing polyp localization methods is a lack of spatio-temporal stability in their response. We propose to explore the response of a given polyp localization across temporal windows in order to select those ima...

Sphenochoanal polyp is a rare form of choanal polyp which originates from the sphenoid sinus and extends to posterior choanae via sphenoethmoidal recess. Its occurrence is extremely rare. They can be easily mistaken for antrochoanal polyp. Symptomatically, it is similar to antrochoanal polyp. So, adequate preoperative evaluation with diagnostic nasal endoscopy and computed tomography or magneti...

Fibroepithelial pharyngeal polyps are rare. We herein report a case of a 56-year-old Asian woman who presented with voice hoarseness and throat discomfort for several years because of a giant pharyngeal polyp. We resected the polyp under general anesthesia. It originated in the left hypopharyngeal wall. Postoperative recovery was uneventful. Her sore throat was diminished within 1 week after th...

A gastric inverted hyperplastic polyp is a rare type of gastric polyp and is characterized by downward growth of a variety of mucosal components into the submucosa. The polyp consists of columnar cells resembling foveolar epithelium and pyloric gland epithelium and can coexist with gastritis cystica profunda. Frequently, adenocarcinoma can coexist, but the relation is not clear. A 77-year-old m...

Polyphosphate (polyP) consists of tens to hundreds of phosphates, linked by ATP-like high-energy bonds. Although polyP is present in mammalian mitochondria, its physiological roles there are obscure. Here, we examine the involvement of polyP in mitochondrial energy metabolism and ion transport. We constructed a vector to express a mitochondrially targeted polyphosphatase, along with a GFP fluor...