The variability observed in many complex gamma-ray bursts (GRBs) is inconsistent with causally connected variations in a single, symmetric, relativistic shell interacting with the ambient material (" external shocks "). Rather, either the central site must produce ∼ 10 50 erg s −1 for hundreds of seconds (" internal shocks ") or the symmetry of the shell must be broken on an angular scale much ...

Alteration of extra-embryonic venous blood flow in stage-17 chick embryos results in well-defined cardiovascular malformations. We hypothesize that the decreased dorsal aortic blood volume flow observed after venous obstruction results in altered ventricular diastolic function in stage-24 chick embryos. A microclip was placed at the right lateral vitelline vein in a stage-17 (52-64 h of incubat...

The effects of developing perinephritic hypertension (2-3 weeks) and a more stable period of perinephritic hypertension (approximately 14 weeks) were examined on indexes of left ventricular (LV) diastolic function in conscious, chronically instrumented dogs. The complete period of diastole was studied using indexes of isovolumic relaxation (tau), early filling (LV +dD/dt), and stiffness (myocar...

Microfluidic channels with integrated pillars are fabricated on SU8 and PDMS substrates to understand the capillary flow. Microscope in conjunction with highspeed camera is used to capture the meniscus front movement through these channels for ethanol and isopropyl alcohol, respectively. In parallel, numerical simulations are conducted, using volume of fluid method, to predict the capillary flo...

In order to solve the bleeding problem of self-flowing tailings filling slurry with low concentration, the influences of the dosage of special additive on the bleeding rate were investigated. The improving mechanism of special additive on the bleeding of tailings filling slurry was studied by measuring the bleeding rate and compressive strength of the slurry. Also, microstruture analysis was co...

The well-established elevation in left ventricular filling pressures during exercise in patients after transplantation may contribute to decreased exercise tolerance. A proposed mechanism for this increase in filling pressures is an abnormal pressure-volume homeostasis of the transplanted heart. Twenty-three patients undergoing routine 1-year evaluations performed supine bicycle exercise during...

We investigate, at a laboratory scale, the collapse of cylindrical shells of radius R and thickness t induced by a granular discharge. We measure the critical filling height for which the structure fails upon discharge. We observe that the silos sustain filling heights significantly above an estimation obtained by coupling standard shell-buckling and granular stress distribution theories. Two e...

A Hilbert space-filling curve is a curve traversing the 2(n) x 2(n)two-dimensional space and it visits neighboring points consecutively without crossing itself. The application of Hilbert space-filling curves in image processing is to rearrange image pixels in order to enhance pixel locality. A computer program of the Hilbert space-filling curve ordering generated from a tensor product formula ...

The consequences of transfusional iron overload on left ventricular diastolic filling have never been investigated systematically in patients with thalassemia major. In the present study, the pattern of left ventricular filling was assessed by Doppler echocardiography in 32 patients with thalassemia major (age, 17 +/- 5 years) who had not experienced symptoms of heart failure and had normal lef...

The aim of this work is to better understand fluid displacement mechanisms at the pore scale in relation to capillary-filling rules. Using specifically designed micro-models we investigate the role of pore body shape on fluid displacement during drainage and imbibition via quasi-static and spontaneous experiments at ambient conditions. The experimental results are directly compared to lattice B...