This article provides a novel method of constructing an optical fiber localized surface plasmon resonance (LSPR) biosensor. A gold nanoparticle (NP) assembled film as the sensing layer was built on the polyelectrolyte (PE) multilayer modified sidewall of an unclad optical fiber. By using a trilayer PE structure, we obtained a monodisperse gold NP assembled film. The preparation procedure for th...

Performing detailed studies of viscoelastic dewetting of thin polystyrene films on solid substrates, we demonstrate the existence of residual stress due to strongly out of equilibrium chain conformations and a reduced entanglement density resulting from film preparation by spin coating. The ratio of stress over elastic modulus was found to increase strongly with decreasing film thickness and in...

Ultrafast time-resolved absorption spectroscopy is used to investigate exciton dynamics in CdSe nanocrystal films. The effects of morphology, quantum-dot versus quantum-rod, and preparation of nanocrystals in a thin film form are investigated. The measurements revealed longer intraband exciton relaxation in quantum-rods than in quantum-dots. The slowed relaxation in quantum-rods is due to mitig...

We have studied, using in situ scanning tunneling microscopy, the morphology of ultrathin quench condensed Au films in the thickness range in which they first become electrically continuous. With increasing thickness, the film evolves from a smooth and nearly featureless morphology, to a single layer of nanoclusters, to a loose pack of multiple layers of nanoclusters. This evolution depends onl...

Amperometric glucose biosensors were constructed by codeposition of glucose oxidase (GOx) with chitosangold (chitosan-AuNP) on gold-Prussian Blue (Au-PB) nanoparticles modified glassy carbon electrodes (GCE). The high stability of the biosensors was achieved using electrochemically controllable in situ Au-PB film preparation following the film covering with GOx layer encrusted with chitosan-AuN...

Over the past few decades, there has been an increased interest for innovative drug delivery systems to improve safety, efficacy and patient compliance, thereby increasing the product patent life cycle. The discovery and development of new chemical entities is not only an expensive but also time consuming affair. Hence the pharmaceutical industries are focusing on the design and development of ...

Intratracheal administration of corticosteroids using a natural pulmonary surfactant as a delivery vehicle has recently received significant attention in hopes of treating premature newborns with or at high risk for chronic lung disease. As a new practice, both the surfactant preparation used as the carrier and the corticosteroid delivered as the anti-inflammatory agent, and their mixing ratios...