BACKGROUND Breast density is a significant breast cancer risk factor measured from mammograms. The most appropriate method for measuring breast density for risk applications is still under investigation. Calibration standardizes mammograms to account for acquisition technique differences prior to making breast density measurements. We evaluated whether a calibration methodology developed for an...

In Brazil, the National Cancer Institute (INCA) reports more than 50,000 new cases of the disease, with risk of 51 cases per 100,000 women. Radiographic images obtained from mammography equipments are one of the most frequently used techniques for helping in early diagnosis. Due to factors related to cost and professional experience, in the last two decades computer systems to support detection...

The accurate segmentation of tumours is a crucial stage diagnosis and treatment, reducing the damage that breast cancer causes, which most common type among women, especially after age forty. task segmenting in mammograms very difficult, as its difficulty lies lack contrast between tumour surrounding tissue, when dealing with small are not clear boundaries hidden under tissues. As algorithms of...

BACKGROUND Previous studies have reported volatile organic compounds (VOCs) in breath as biomarkers of breast cancer and abnormal mammograms, apparently resulting from increased oxidative stress and cytochrome p450 induction. We evaluated a six-minute point-of-care breath test for VOC biomarkers in women screened for breast cancer at centers in the USA and the Netherlands. METHODS 244 women h...

BACKGROUND The cumulative risk of a false-positive mammogram can be substantial. We studied which variables affect the chance of a false-positive mammogram and estimated cumulative risks over nine sequential mammograms. METHODS We used medical records of 2227 randomly selected women who were 40-69 years of age on July 1, 1983, and had at least one screening mammogram. We used a Bayesian discr...

BACKGROUND Mammographic screening is carried out at public sector hospitals as part of clinical practice. OBJECTIVE We report the experience of such screening at Tygerberg Academic Hospital (TBAH), a tertiary referral hospital in the Western Cape Province, South Africa. METHODS All mammograms performed between 2003 and 2012 at TBAH were analysed regarding patient demographics, clinical data...

Breast cancer is currently one of the major causes of death for women in the U.S. Mammography is currently the most effective method for detection of breast cancer and early detection has proven to be an efficient tool to reduce the number of deaths. Mammography is the most demanding of all clinical imaging applications as it requires high contrast, high signal to noise ratio and resolution wit...

One of the parameters that are usually stored for mammograms is the BI-RADS density, which gives an idea of the breast tissue composition. In this work, we study the effect of BI-RADS density in our ongoing project for developing an image-based CAD system to detect masses in mammograms. This system consists of two stages. First, a blind feature extraction is performed for regions of interest (R...